S
Susan K. Fried
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 142
Citations - 15376
Susan K. Fried is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Adipose tissue & Adipocyte. The author has an hindex of 62, co-authored 135 publications receiving 14112 citations. Previous affiliations of Susan K. Fried include University of Medicine and Dentistry of New Jersey & Rockefeller University.
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Journal ArticleDOI
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid.
TL;DR: These data show for the first time that substantial quantities of IL-6 (up to 75 ng/mL) accumulate in the medium during incubations of both adipocytes and adipose tissue.
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Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action
Rongze Yang,Mi-Jeong Lee,Hong Hu,Jessica Pray,Hai-Bin Wu,Barbara C. Hansen,Alan R. Shuldiner,Susan K. Fried,John C. McLenithan,Da-Wei Gong +9 more
TL;DR: Central obesity is more closely associated with insulin resistance, type 2 diabetes, and cardiovascular disease than is peripheral obesity, but the underlying mechani... as discussed by the authors showed that central (visceral) obesity is associated with Type 2 diabetes.
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Omentin Plasma Levels and Gene Expression Are Decreased in Obesity
Celia M. De Souza Batista,Rong Ze Yang,Mi-Jeong Lee,Nicole M. Glynn,Dao Zhan Yu,Jessica Pray,Kelechi Ndubuizu,Susheel P. Patil,Alan L. Schwartz,Mark D. Kligman,Susan K. Fried,Susan K. Fried,Da-Wei Gong,Alan R. Shuldiner,Alan R. Shuldiner,Toni I. Pollin,John C. McLenithan,John C. McLenithan +17 more
TL;DR: Omentin 1 and omentin 2 gene expression were decreased with obesity and were highly correlated with each other in visceral adipose tissue as mentioned in this paper, indicating that decreased Omentin levels are associated with increasing obesity and insulin resistance.
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Regulatory role for the arginine–nitric oxide pathway in metabolism of energy substrates
Wenjuan S. Jobgen,Susan K. Fried,Wenjiang J. Fu,Cynthia J. Meininger,Guoyao Wu,Guoyao Wu,Guoyao Wu +6 more
TL;DR: Modulation of the arginine-NO pathway through dietary supplementation with L-arginine or L-citrulline may aid in the prevention and treatment of the metabolic syndrome in obese humans and companion animals, and in reducing unfavorable fat mass in animals of agricultural importance.
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Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications.
TL;DR: This chapter will review the phenotypic characteristics of different adipose depots and mechanisms that link their depot-specific biology to metabolic complications in men and women.