D
Dace V. Madore
Researcher at University of Rochester
Publications - 38
Citations - 4713
Dace V. Madore is an academic researcher from University of Rochester. The author has contributed to research in topics: Vaccination & Conjugate vaccine. The author has an hindex of 26, co-authored 38 publications receiving 4652 citations. Previous affiliations of Dace V. Madore include State University of New York System.
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Journal ArticleDOI
Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children
Steven Black,Henry R. Shinefield,Bruce Fireman,Edwin Lewis,Paula Ray,John Hansen,Laura Elvin,Kathy M. Ensor,Jill G. Hackell,George R. Siber,Frank J. Malinoski,Dace V. Madore,Ih Chang,Robert Kohberger,Wendy J. Watson,Robert Austrian,Kathy Edwards +16 more
TL;DR: The Wyeth Lederle as discussed by the authors determined the efficacy, safety and immunogenicity of the CRM197 pneumococcal conjugate vaccine against invasive disease caused by vaccine serotypes and to determine the effectiveness of this vaccine against clinical episodes of otitis media.
Journal ArticleDOI
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants.
Margaret B. Rennels,Kathryn M. Edwards,Harry L. Keyserling,Keith S. Reisinger,Hogerman Deborah A,Dace V. Madore,Ih Chang,Peter R. Paradiso,Frank J. Malinoski,Alan Kimura +9 more
TL;DR: Primary immunization followed by a booster dose of PNCRM7 seemed to be acceptably safe and resulted in significant rises in antibody to all 7 serotypes, demonstrating effective stimulation of T-cell memory by the primary series of vaccinations.
Journal ArticleDOI
Enzyme-linked immunosorbent assay for quantitation of human antibodies to pneumococcal polysaccharides.
Catherine M. Wernette,Carl E. Frasch,Dace V. Madore,George M. Carlone,David Goldblatt,Brian D. Plikaytis,William H. Benjamin,Sally A. Quataert,Steve Hildreth,Daniel J. Sikkema,Helena Käyhty,Ingileif Jonsdottir,Moon H. Nahm +12 more
TL;DR: Streptococcus pneumoniae is a major human pathogen causing pneumonia, sepsis, meningitis, and otitis media, and elderly adults because their immune systems are either unprepared or unable to respond effectively to it.
Journal ArticleDOI
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers.
Henry R. Shinefield,Steven Black,Paula Ray,Ih Chang,Ned Lewis,Bruce Fireman,Jill G. Hackell,Peter R. Paradiso,George R. Siber,Robert Kohberger,Dace V. Madore,Frank J. Malinowski,Alan Kimura,Chinh Le,Irene Landaw,Janet Aguilar,John Hansen +16 more
TL;DR: It is concluded that PNCRM7 vaccine was safe and immunogenic and when this vaccine was administered concurrently at the booster dose with DTaP and HbOC vaccines, lower antibody titers were noted for some of the antigens when compared with the antibody response when PNC RM7 was given separately.
Journal ArticleDOI
An ELISA employing a Haemophilus influenzae type b oligosaccharide-human serum albumin conjugate correlates with the radioantigen binding assay.
TL;DR: The HbO-HA ELISA can be substituted for the classical RABA and also be utilized for quantitating the isotype of the anti-HbPs antibodies by using isotype specific enzyme conjugates.