D
Dae-Sik Hwang
Researcher at Sungkyunkwan University
Publications - 85
Citations - 3609
Dae-Sik Hwang is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Genome & Mitochondrial DNA. The author has an hindex of 29, co-authored 85 publications receiving 2909 citations. Previous affiliations of Dae-Sik Hwang include Hanyang University & UPRRP College of Natural Sciences.
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Journal ArticleDOI
Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer (Brachionus koreanus)
Chang-Bum Jeong,Chang-Bum Jeong,Eun-Ji Won,Eun-Ji Won,Hye-Min Kang,Min-Chul Lee,Dae-Sik Hwang,Un Ki Hwang,Bingsheng Zhou,Sami Souissi,Su Jae Lee,Jae-Seong Lee +11 more
TL;DR: In vitro tests revealed that antioxidant-related enzymes and MAPK signaling pathways were significantly activated in response to microplastic exposure in a size-dependent manner, suggesting that 6-μm microbeads are more effectively egested from B. koreanus than 0.05- or 0.5- μm microBeads.
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Adverse effects of microplastics and oxidative stress-induced MAPK/Nrf2 pathway-mediated defense mechanisms in the marine copepod Paracyclopina nana.
Chang-Bum Jeong,Hye-Min Kang,Min-Chul Lee,Duck-Hyun Kim,Jeonghoon Han,Dae-Sik Hwang,Sami Souissi,Su Jae Lee,Kyung-Hoon Shin,Heum Gi Park,Jae-Seong Lee +10 more
TL;DR: This study provides the first insight into the mode of action in terms of microplastic-induced oxidative stress and related signaling pathways in P. nana, and proposes an adverse outcome pathway for microplastics exposure that covers molecular and individual levels.
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Estimation of divergence times in cnidarian evolution based on mitochondrial protein-coding genes and the fossil record.
TL;DR: The molecular evidence suggests that cnidarians originated 741 million years ago (Ma) (95% credible region of 686-819), and the major taxa diversified prior to the Cambrian (543 Ma).
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Expression of glutathione S-transferase (GST) genes in the marine copepod Tigriopus japonicus exposed to trace metals.
Kyun-Woo Lee,Sheikh Raisuddin,Sheikh Raisuddin,Jae-Sung Rhee,Dae-Sik Hwang,In Tag Yu,Young-Mi Lee,Heum Gi Park,Jae-Seong Lee +8 more
TL;DR: Findings imply an antioxidant role for GSTS and highlight its importance as a biomarker of exposure to trace metals in T. japonicus, although for some trace metals such as silver the response was not consistent in concentration and time-series exposure experiments.
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Environmental stressors (salinity, heavy metals, H2O2) modulate expression of glutathione reductase (GR) gene from the intertidal copepod Tigriopus japonicus.
Jung Soo Seo,Kyun-Woo Lee,Jae-Sung Rhee,Dae-Sik Hwang,Young-Mi Lee,Heum Gi Park,In-Young Ahn,Jae-Seong Lee +7 more
TL;DR: Slight down-regulation in the expression of Tigriopus GR at the initial stage was observed upon exposure to hydrogen peroxide, and these findings provide a better understanding of cellular protection mechanisms in the intertidal copepod T. japonicus against the environmental stressors caused by non-optimal salt levels.