Dai Fei Elmer Ker

TL;DR: This paper proposes an effective approach for automated mitosis detection using phase-contrast time-lapse microscopy, which is a nondestructive imaging modality, thereby allowing continuous monitoring of cells in culture.

TL;DR: In this paper, the authors discuss aspects of development, healing process, structure, and tissue engineering considerations between calvarial and long bones to assist in designing the tailored bone repair strategies, and propose that tailored tissue engineering strategies, such as scaffold features, growth factor usage, and the source of cells for tissue or region-specific bone repair, are necessary to ensure an optimized healing outcome.

TL;DR: UV‐crosslinkable polyurethane based on quadrol, hexamethylene diisocyante, and methacrylic anhydride, which is free of solvent, catalyst, and photoinitiator, is developed and demonstrates functionally graded, bone‐tendon‐like biomaterials for interfacial tissue engineering.

TL;DR: 48 time-lapse image sequences were generated with accompanying ground truths for C2C12 myoblast cells cultured under 4 different media conditions, including with fibroblast growth factor 2 (FGF2), bone morphogenetic protein 2 (BMP2), FGF2, BMP2, and control, providing an invaluable opportunity to deepen the understanding of individual and population-based cell dynamics for biomedical research.

TL;DR: An image analysis method to detect apoptosis in time-lapse phase-contrast microscopy, which is nondestructive imaging and achieved around 90% accuracy in terms of average precision and recall.