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Dan Li

Researcher at Zhejiang University

Publications -  33
Citations -  868

Dan Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Colorectal cancer & Breast cancer. The author has an hindex of 12, co-authored 28 publications receiving 664 citations. Previous affiliations of Dan Li include Chinese Ministry of Education & Beijing Genomics Institute.

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A distinct metabolic signature of human colorectal cancer with prognostic potential

TL;DR: A panel of 15 significantly altered metabolites was identified, which demonstrates the ability to predict the rate of recurrence and survival for patients after surgery and chemotherapy, and is due to robust metabolic adaptations in cancer cells to increased oxidative stress as well as demand for energy, and macromolecular substrates for cell growth and proliferation.
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MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility.

TL;DR: Ectopic expression of miR-9 enhanced the motility of RKO cells as well as changed their morphological appearance, while cell growth remained unchanged, suggesting that miR -9 may potentially participate in the metastatic process of CRC though facilitating cell motility.
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Predictors and Risk Factors of Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer: A Population-Based Analysis.

TL;DR: Mucinous adenocarcinoma, positive pre-treatment serum CEA results, and clinical T4 and N2 stages may impart difficulty for patients to achieve pCR, and histology and clinical N2 stage were independent risk factors.