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Dan Li
Researcher at Zhejiang University
Publications - 33
Citations - 868
Dan Li is an academic researcher from Zhejiang University. The author has contributed to research in topics: Colorectal cancer & Breast cancer. The author has an hindex of 12, co-authored 28 publications receiving 664 citations. Previous affiliations of Dan Li include Chinese Ministry of Education & Beijing Genomics Institute.
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Journal ArticleDOI
Genome sequencing of the high oil crop sesame provides insight into oil biosynthesis
Linhai Wang,Sheng Yu,Chaobo Tong,Yingzhong Zhao,Yan Liu,Chi Song,Yanxin Zhang,Xudong Zhang,Ying Wang,Wei Hua,Donghua Li,Dan Li,Fang Li,Jingyin Yu,Chunyan Xu,Xuelian Han,Shunmou Huang,Shuaishuai Tai,Junyi Wang,Xun Xu,Yingrui Li,Shengyi Liu,Rajeev K. Varshney,Rajeev K. Varshney,Jun Wang,Jun Wang,Xiurong Zhang +26 more
TL;DR: The sesame genome will facilitate future research on the evolution of eudicots, as well as the study of lipid biosynthesis and potential genetic improvement of sesame, an important species from the order Lamiales and a high oil crop.
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A distinct metabolic signature of human colorectal cancer with prognostic potential
Yunping Qiu,Yunping Qiu,Guoxiang Cai,Bingsen Zhou,Dan Li,Aihua Zhao,Guoxiang Xie,Houkai Li,Sanjun Cai,Dong Xie,Changzhi Huang,Weiting Ge,Zhanxiang Zhou,Lisa X. Xu,Weiping Jia,Shu Zheng,Yun Yen,Wei Jia,Wei Jia +18 more
TL;DR: A panel of 15 significantly altered metabolites was identified, which demonstrates the ability to predict the rate of recurrence and survival for patients after surgery and chemotherapy, and is due to robust metabolic adaptations in cancer cells to increased oxidative stress as well as demand for energy, and macromolecular substrates for cell growth and proliferation.
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MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility.
TL;DR: Ectopic expression of miR-9 enhanced the motility of RKO cells as well as changed their morphological appearance, while cell growth remained unchanged, suggesting that miR -9 may potentially participate in the metastatic process of CRC though facilitating cell motility.
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Predictors and Risk Factors of Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer: A Population-Based Analysis.
TL;DR: Mucinous adenocarcinoma, positive pre-treatment serum CEA results, and clinical T4 and N2 stages may impart difficulty for patients to achieve pCR, and histology and clinical N2 stage were independent risk factors.
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Exome capture sequencing of adenoma reveals genetic alterations in multiple cellular pathways at the early stage of colorectal tumorigenesis.
Donger Zhou,Donger Zhou,Liu Yang,Liu Yang,Liangtao Zheng,Liangtao Zheng,Weiting Ge,Weiting Ge,Dan Li,Dan Li,Yong Zhang,Xueda Hu,Zhibo Gao,Jinghong Xu,Yanqin Huang,Yanqin Huang,Hanguang Hu,Hanguang Hu,Hang Zhang,Hang Zhang,Hao Zhang,Mingming Liu,Huanming Yang,Lei Zheng,Lei Zheng,Shu Zheng,Shu Zheng +26 more
TL;DR: Comparison of genomic mutations between adenoma and adenocarcinoma provides a new insight into the molecular events governing the early step of colorectal tumorigenesis.