D
Dana Ghanem
Researcher at Lawrence Berkeley National Laboratory
Publications - 3
Citations - 415
Dana Ghanem is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Alternative splicing & Exon. The author has an hindex of 2, co-authored 3 publications receiving 351 citations.
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Journal ArticleDOI
Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges
Michael T. Lovci,Dana Ghanem,Henry Marr,Justin K. Arnold,Sherry Gee,Marilyn Parra,Tiffany Y. Liang,Thomas J. Stark,Lauren T Gehman,Shawn Hoon,Shawn Hoon,Katlin B. Massirer,Gabriel A. Pratt,Douglas L. Black,Joe W. Gray,John G. Conboy,Gene W. Yeo +16 more
TL;DR: It is shown here that binding in distal intronic regions by Rbfox splicing factors important in development is extensive and is an active mode of splicing regulation.
Journal ArticleDOI
A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis
Harold Pimentel,Marilynn Parra,Sherry Gee,Dana Ghanem,Xiuli An,Jie Li,Narla Mohandas,Lior Pachter,John G. Conboy +8 more
TL;DR: It is concluded that a highly dynamic alternative splicing program in terminally differentiating erythroblasts plays a major role in regulating gene expression to ensure synthesis of appropriate proteome at each stage as the cells remodel in preparation for production of mature red cells.
Journal ArticleDOI
A Dynamic Alternative Splicing Program Regulates Gene Expression In A Differentiation Stage-Specific Manner During Terminal Erythropoiesis
Harold Pimentel,Marilyn Parra,Jie Li,Sherry Gee,Dana Ghanem,Jingping Hu,Xiuli An,Mohandas Narla,Lior Pachter,John G. Conboy +9 more
TL;DR: It is concluded that a dynamically regulated alternative splicing program in terminally differentiating erythroblasts plays a major post-transcriptional role in shaping gene expression as the cells transition from proliferation to differentiation.