D
Daniël P. Melters
Researcher at National Institutes of Health
Publications - 27
Citations - 989
Daniël P. Melters is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Chromatin & Nucleosome. The author has an hindex of 8, co-authored 20 publications receiving 815 citations. Previous affiliations of Daniël P. Melters include University of California, Davis & University of California, San Francisco.
Papers
More filters
Journal ArticleDOI
Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution.
Daniël P. Melters,Keith Bradnam,Hugh A. Young,Natalie Telis,Michael R. May,J. Graham Ruby,Robert Sebra,Paul Peluso,John Eid,David R. Rank,José Fernando Garcia,Joseph L. DeRisi,Joseph L. DeRisi,Timothy P. L. Smith,Christian M. Tobias,Jeffrey Ross-Ibarra,Ian F Korf,Simon W. L. Chan,Simon W. L. Chan +18 more
TL;DR: The results indicate that tandem repeats are highly prevalent at centromeres of both animal and plant genomes, which suggests a functional role for such repeats, perhaps in promoting concerted evolution of centromere DNA across chromosomes.
Journal ArticleDOI
Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis
TL;DR: This review describes how holocentricity may be identified through cytological and molecular methods and how extensive genome sequencing and experiments in nonmodel organisms may allow Holocentric chromosomes to shed light on general principles of chromosome segregation.
Journal ArticleDOI
Epithelial sodium channel regulated by differential composition of a signaling complex.
TL;DR: GILZ1 and SGK1 are suggested to provide a physical and functional link between the PI3K- and Raf-1-dependent signaling modules and represent a unique mechanism for specifically controlling Na+ transport without inappropriately activating other cell functions.
Journal ArticleDOI
Differential activities of glucocorticoid-induced leucine zipper protein isoforms.
TL;DR: GILZ inhibition of ERK appears to play an essential role in stimulation of cell surface ENaC but not in inhibition of proliferation, and rat and mouse tissues all expressed multiple GILZ species but varied in the relative abundance of each.
Journal ArticleDOI
Glucocorticoid-induced Leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization.
TL;DR: It is shown that the aldosterone-induced chaperone, GILZ1 (glucocorticoid-induced leucine zipper protein-1) selectively decreases SGK1 localization to ER as well as its interaction with ER-associated E3 ubiquitin ligases, HRD1 and CHIP.