D
Daniel Teupser
Researcher at Ludwig Maximilian University of Munich
Publications - 121
Citations - 6781
Daniel Teupser is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 35, co-authored 99 publications receiving 4851 citations. Previous affiliations of Daniel Teupser include Leipzig University & University of Kiel.
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Journal ArticleDOI
Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans.
Lesca M. Holdt,Anika Stahringer,Kristina Sass,Garwin Pichler,Nils A. Kulak,Wolfgang Wilfert,Alexander Kohlmaier,Andreas Herbst,Bernd H. Northoff,Alexandros Nicolaou,Gabor Gäbel,Frank Beutner,Markus Scholz,Joachim Thiery,Kiran Musunuru,Knut Krohn,Matthias Mann,Daniel Teupser,Daniel Teupser +18 more
TL;DR: These findings identify circANRIL as a prototype of a circRNA regulating ribosome biogenesis and conferring atheroprotection, thereby showing that circularization of long non-coding RNAs may alter RNA function and protect from human disease.
Journal ArticleDOI
Revisiting biomarker discovery by plasma proteomics.
TL;DR: A “rectangular” plasma proteome profiling strategy is proposed, in which the proteome patterns of large cohorts are correlated with their phenotypes in health and disease.
Journal ArticleDOI
Plasma Proteome Profiling to Assess Human Health and Disease.
Philipp E. Geyer,Nils A. Kulak,Garwin Pichler,Lesca M. Holdt,Daniel Teupser,Matthias Mann,Matthias Mann +6 more
TL;DR: A rapid and robust "plasma proteome profiling" pipeline is introduced that enables quantitative analysis of hundreds of plasma proteomes from 1 μl single finger pricks with 20 min gradients and functionally interpret a 1,000-protein, quantitative plasma proteome obtained by simple peptide pre-fractionation.
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Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.
Leo Nicolai,Alexander Leunig,Sophia Brambs,Rainer Kaiser,Tobias Weinberger,Michael Weigand,Maximilian Muenchhoff,Johannes C. Hellmuth,Stephan Ledderose,Heiko Schulz,Clemens Scherer,Martina Rudelius,Michael Zoller,Dominik Höchter,Oliver T. Keppler,Daniel Teupser,Bernhard Zwißler,Michael von Bergwelt-Baildon,Stefan Kääb,Steffen Massberg,Kami Pekayvaz,Konstantin Stark +21 more
TL;DR: Evidence is provided that organ involvement and prothrombotic features in COVID-19 are linked by immunothrombosis, and data point to immunothROMbotic dysregulation as a key marker of disease severity in CO VID-19.
Journal ArticleDOI
Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks
Lesca M. Holdt,Steve Hoffmann,Kristina Sass,David Langenberger,Markus Scholz,Knut Krohn,Knut Finstermeier,Anika Stahringer,Wolfgang Wilfert,Frank Beutner,Stephan Gielen,Gerhard Schuler,Gabor Gäbel,Hendrik Bergert,Ingo Bechmann,Peter F. Stadler,Joachim Thiery,Daniel Teupser,Daniel Teupser +18 more
TL;DR: This study provides a molecular mechanism for pro-atherogenic effects of ANRIL at Chr9p21 and suggests a novel role for Alu elements in epigenetic gene regulation by long ncRNAs.