D
Daniel Trageser
Researcher at University of Bonn
Publications - 9
Citations - 668
Daniel Trageser is an academic researcher from University of Bonn. The author has contributed to research in topics: Stem cell & Cancer stem cell. The author has an hindex of 7, co-authored 8 publications receiving 586 citations.
Papers
More filters
Journal ArticleDOI
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.
Yunqing Li,Angela Li,Martin Glas,Bachchu Lal,Bachchu Lal,Mingyao Ying,Mingyao Ying,Yingying Sang,Shuli Xia,Shuli Xia,Daniel Trageser,Hugo Guerrero-Cazares,Charles G. Eberhart,Alfredo Quiñones-Hinojosa,Björn Scheffler,John Laterra,John Laterra +16 more
TL;DR: In this article, the tyrosine kinase c-Met activation was found to induce the expression of reprogramming transcription factors known to support embryonic stem cells and induce differentiated cells to form pluripotent stem (iPS) cells.
Journal ArticleDOI
Anticancer Effects of Niclosamide in Human Glioblastoma
Anja Wieland,Daniel Trageser,Sabine Gogolok,Roman Reinartz,Heike Höfer,Mihaela Keller,Anke Leinhaas,Ramona Schelle,Sabine Normann,Lil Klaas,Andreas Waha,Philipp Koch,Rolf Fimmers,Torsten Pietsch,Anthony T. Yachnis,David W. Pincus,Dennis A. Steindler,Oliver Brüstle,Matthias Simon,Martin Glas,Björn Scheffler +20 more
TL;DR: Together, the data advocate the use of pGBMs for exploration of compound libraries to reveal unexpected leads, for example, niclosamide that might be suited for further development toward personalized clinical application.
Journal ArticleDOI
Residual tumor cells are unique cellular targets in glioblastoma
Martin Glas,Barbara H. Rath,Matthias Simon,Roman Reinartz,Anja Schramme,Daniel Trageser,Ramona Eisenreich,Anke Leinhaas,Mihaela Keller,Hans-Ulrich Schildhaus,Stephan Garbe,Barbara Steinfarz,Torsten Pietsch,Dennis A. Steindler,Johannes Schramm,Ulrich Herrlinger,Oliver Brüstle,Björn Scheffler +17 more
TL;DR: In vitro analysis of proliferation, invasion, stem cell qualities, GBM‐typical antigens, genotypes, and in vitro drug and irradiation challenge studies revealed residual tumor cells as unique entities.
Journal ArticleDOI
The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells
Dat T. Vo,Kotb Abdelmohsen,Jennifer L. Martindale,Mei Qiao,Kumiko Tominaga,Tarea L. Burton,Jonathan Gelfond,Andrew Brenner,Vyomesh Patel,Daniel Trageser,Björn Scheffler,Myriam Gorospe,Luiz O. F. Penalva +12 more
TL;DR: It is suggested that HuR is an important regulator of Msi1 in glioblastoma and that this regulation has important biological consequences during gliomagenesis.
Journal ArticleDOI
Targeting the Cytosolic Innate Immune Receptors RIG-I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma
Martin Glas,Christoph Coch,Daniel Trageser,Juliane Daßler,Matthias Simon,Philipp Koch,Jerome Mertens,Tamara Quandel,Raphaela Gorris,Roman Reinartz,Anja Wieland,Marec von Lehe,Annette Pusch,Kristin Roy,Martin Schlee,Harald Neumann,Rolf Fimmers,Ulrich Herrlinger,Oliver Brüstle,Gunther Hartmann,Robert Besch,Björn Scheffler +21 more
TL;DR: Activation of the innate immune system by stimulation of innate immune receptors involved in antiviral and antitumor responses can similarly target different malignant populations of glioma cells.