M
Mei Qiao
Researcher at University of Texas Health Science Center at San Antonio
Publications - 38
Citations - 3605
Mei Qiao is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: RNA-binding protein & Gene. The author has an hindex of 22, co-authored 36 publications receiving 3065 citations. Previous affiliations of Mei Qiao include Greehey Children's Cancer Research Institute.
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Journal ArticleDOI
A compendium of RNA-binding motifs for decoding gene regulation
Debashish Ray,Hilal Kazan,Kate B. Cook,Matthew T. Weirauch,Matthew T. Weirauch,Hamed S. Najafabadi,Xiao Li,Serge Gueroussov,Mihai Albu,Hong Zheng,Ally Yang,Hong Na,Manuel Irimia,Leah H. Matzat,Ryan K. Dale,Sarah A. Smith,Christopher A. Yarosh,Seth M. Kelly,Behnam Nabet,D. Mecenas,Weimin Li,Rakesh S. Laishram,Mei Qiao,Howard D. Lipshitz,Fabio Piano,Anita H. Corbett,Russ P. Carstens,Brendan J. Frey,Richard A. Anderson,Kristen W. Lynch,Luiz O. F. Penalva,Elissa P. Lei,Andrew G. Fraser,Benjamin J. Blencowe,Quaid Morris,Timothy P. Hughes +35 more
TL;DR: A systematic analysis of the RNA motifs recognized by RNA-binding proteins, encompassing 205 distinct genes from 24 diverse eukaryotes, provides an unprecedented overview of RNA- binding proteins and their targets, and constitute an invaluable resource for determining post-transcriptional regulatory mechanisms in eukARYotes.
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E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation
TL;DR: Smurf1 appears to be an important regulatory factor in osteoblast differentiation and a potential molecular target for identification of bone anabolic agents.
Journal ArticleDOI
Site identification in high-throughput RNA–protein interaction data
Philip J. Uren,Emad Bahrami-Samani,Suzanne C. Burns,Mei Qiao,Fedor V. Karginov,Emily Hodges,Gregory J. Hannon,Jeremy R. Sanford,Luiz O. F. Penalva,Andrew D. Smith +9 more
TL;DR: This work introduces a method for site identification which can be applied on all variations of CLIP and RIP-seq technologies, and accurately models the underlying read-count distributions, and allows external covariates, such as transcript abundance, to inform the site identification process.
Journal ArticleDOI
Before It Gets Started: Regulating Translation at the 5' UTR.
Patrícia R. Araújo,Kihoon Yoon,Daijin Ko,Andrew D. Smith,Mei Qiao,Uthra Suresh,Suzanne C. Burns,Luiz O. F. Penalva,Luiz O. F. Penalva +8 more
TL;DR: Important aspects of 5′ UTR-mediated regulation are discussed by providing an overview of the characteristics and the function of the main elements present in this region, like uORF (upstream open reading frame), secondary structures, and RBPs binding motifs and different mechanisms of translation regulation.
Journal ArticleDOI
Smurf1 Inhibits Osteoblast Differentiation and Bone Formation in Vitro and in Vivo
TL;DR: The results demonstrate for the first time that Smurf1 plays a specific role in osteoblast differentiation and bone formation in vivo.