D
Daniela Dick-Necula
Researcher at Sheba Medical Center
Publications - 5
Citations - 661
Daniela Dick-Necula is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Cancer & Internal medicine. The author has an hindex of 3, co-authored 4 publications receiving 159 citations.
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Journal ArticleDOI
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
Erez N. Baruch,Erez N. Baruch,Ilan Youngster,Guy Ben-Betzalel,Rona Ortenberg,Adi Lahat,Lior H. Katz,Katerina Adler,Daniela Dick-Necula,Stephen P. Raskin,Stephen P. Raskin,Naamah Bloch,Daniil Rotin,Liat Anafi,Camila Avivi,Jenny Melnichenko,Yael Steinberg-Silman,Ronac Mamtani,Hagit Harati,Nethanel Asher,Ronnie Shapira-Frommer,Tal Brosh-Nissimov,Yael Eshet,Yael Eshet,Shira Ben-Simon,Oren Ziv,Abdul Wadud Khan,Moran Amit,Nadim J. Ajami,Iris Barshack,Iris Barshack,Jacob Schachter,Jacob Schachter,Jennifer A. Wargo,Omry Koren,Gal Markel,Gal Markel,Ben Boursi,Ben Boursi,Ben Boursi +39 more
TL;DR: Treatment with FMT was associated with favorable changes in immune cell infiltrates and gene expression profiles in both the gut lamina propria and the tumor microenvironment, which have implications for modulating the gut microbiota in cancer treatment.
Journal ArticleDOI
Correction to: ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis.
Adi Zundelevich,Maya Dadiani,Smadar Kahana-Edwin,Amit Itay,Tal Sella,Moran Gadot,Karen Cesarkas,Sarit Farage-Barhom,Efrat Glick Saar,Eran Eyal,Nitzan Kol,Anya Pavlovski,Nora Balint-Lahat,Daniela Dick-Necula,Iris Barshack,Iris Barshack,Bella Kaufman,Bella Kaufman,Einav Nili Gal-Yam +18 more
TL;DR: After the publication of the original article, the upper panel of the Fig. 1, where the patients’ codes are listed, was cropped by mistake so the patients 1–8 are repeated.
Proceedings ArticleDOI
Abstract CT042: Fecal microbiota transplantation (FMT) and re-induction of anti-PD-1 therapy in refractory metastatic melanoma patients - preliminary results from a phase I clinical trial (NCT03353402)
Erez N. Baruch,Ilan Youngster,Rona Ortenberg,Guy Ben-Betzalel,Lior H. Katz,Adi Lahat,Iris Barshack,Daniela Dick-Necula,Ronac Mamtani,Naamah Bloch,Bella Ungar,Daniel Rotin,Camila Avivi,Liat Anafi,Yael Steinberg-Silman,Nethanel Asher,Ronnie Shapira-Frommer,Tal Brosh-Nissimov,Yael Eshet,Stephen Raskin,Hagit Harati,Jenny Melnichenko,Jacob Schachter,Omry Koren,Gal Markel,Ben Boursi +25 more
TL;DR: FMT in metastatic melanoma patients seemed to be safe and may alter recipient gut microbiota to resemble that of a responder donor, which was translated to a clinical and radiological benefit in two recipients.
Journal ArticleDOI
Immune co-culture cell microarray - a feasible tool for high-throughput functional investigation of lymphocyte-cancer interactions.
Erez N. Baruch,Erez N. Baruch,Rona Ortenberg,Camila Avivi,Liat Anafi,Daniela Dick-Necula,Chani Stossel,Chani Stossel,Yonatan Moshkovits,Orit Itzhaki,Michal J. Besser,Michal J. Besser,Jacob Schachter,Jacob Schachter,Iris Barshack,Iris Barshack,Gal Markel,Gal Markel +17 more
TL;DR: Functional dynamics assessment of both proteins and microRNAs using ICCM stained slides demonstrated similar findings to flow cytometry assays and to previously published patient-derived biopsy reports.
Journal ArticleDOI
Evaluation of ovarian reserve in young females with non-iatrogenic ovarian insufficiency to establish criteria for ovarian tissue cryopreservation.
Michal Zajicek,Alexander Volodarsky-Perel,Daniel Shai,Daniela Dick-Necula,Hila Raanani,Noah Gruber,Gideon Karplus,Eran Kassif,Boaz Weisz,Dror Meirow +9 more
TL;DR: In this article , ovarian reserve parameters predict the outcome of ovarian tissue cryopreservation (OTCP) in patients ≤18 years with non-iatrogenic premature ovarian insufficiency (POI).