Daniela Matarrese

TL;DR: Graphical abstract Image, graphical abstract images showing how the model transformed from a discrete-time model to a 3D model with real-time consequences has changed over time.

TL;DR: It is found that baricitinib exerts activity rapidly through the inhibition of host proteins (numb-associated kinases), uniquely among antivirals, and is associated with beneficial outcomes including in severely ill elderly patients, data that incentivize further randomized controlled trials.

TL;DR: Baricitinib, an anti-JAK1/JAK2, reduces cytokine release and SARS-Co-V2 entry and reduces COVID-19 mortality rate in a retrospective multicenter study and reduces intensive care unit admissions of CO VID-19 pneumonia.

TL;DR: Identification and stabilization of concomitant clinical problems by internal medicine specialists may safely decrease time to surgery in frail subjects with hip fracture and integrate perioperative clinical management may shorten hospital stay with no apparent increase in in-hospital mortality and ultimately improve the outcome.

TL;DR: The first year of the CCM implementation had a significant impact on the diabetes care indicator, and performance was stabilized after the first year, while impact on therapy indicator was smaller.