D
Daniela Varges
Researcher at University of Göttingen
Publications - 48
Citations - 2414
Daniela Varges is an academic researcher from University of Göttingen. The author has contributed to research in topics: Dementia & Dementia with Lewy bodies. The author has an hindex of 23, co-authored 43 publications receiving 2033 citations. Previous affiliations of Daniela Varges include German Center for Neurodegenerative Diseases.
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Journal ArticleDOI
Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease
Inga Zerr,Kai Kallenberg,David Summers,C. Romero,Ana Lia Taratuto,Uta Heinemann,Maren Breithaupt,Daniela Varges,Bettina Meissner,Anna Ladogana,Maaike Schuur,Stéphane Haïk,Steven J. Collins,Gerard H. Jansen,G. B. Stokin,José Pimentel,Ekkehard Hewer,D. Collie,Pete Smith,H. Roberts,Jean-Philippe Brandel,C M van Duijn,Maurizio Pocchiari,C. Begue,Patrick Cras,Robert G. Will,Pascual Sánchez-Juan +26 more
TL;DR: Cerebral cortical signal increase and high signal in caudate nucleus and putamen on fluid attenuated inversion recovery or diffusion-weight imaging magnetic resonance imaging are useful in the diagnosis of sporadic Creutzfeldt–Jakob disease.
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Creutzfeldt-Jakob disease in Germany: a prospective 12-year surveillance.
Uta Heinemann,Anna Krasnianski,Bettina Meissner,Daniela Varges,Kai Kallenberg,Walter J. Schulz-Schaeffer,Bernhard J. Steinhoff,E. M. Grasbon-Frodl,Hans A. Kretzschmar,Inga Zerr +9 more
TL;DR: Since 1993, there has been an increasing incidence of CJD, from 0.7 in 1993 to 1.6 in 2005 with a quite stable level since 1998, during this period, the proportion of patients with MV and VV codon 129 genotype rose, possibly because of better identification of atypical subtypes.
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Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease.
Maria Cramm,Matthias Schmitz,André Karch,Eva Mitrova,Franziska Kuhn,Bjoern Schroeder,Alex Raeber,Daniela Varges,Yong-Sun Kim,Katsuya Satoh,Steven J. Collins,Inga Zerr +11 more
TL;DR: The present study underlines the reproducibility and high stability of RT-QuIC across various CSF storage conditions with a remarkable sensitivity and specificity, suggesting RT- QuIC as an innovative and robust diagnostic method.
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Characteristic CSF prion seeding efficiency in humans with prion diseases.
Maria Cramm,Matthias Schmitz,André Karch,Saima Zafar,Daniela Varges,Eva Mitrova,Bjoern Schroeder,Alex Raeber,Franziska Kuhn,Inga Zerr +9 more
TL;DR: It is demonstrated that PrPSc characteristics in the CSF of human prion disease patients are associated with disease subtypes and rate of decline as defined by disease duration.
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Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD.
Anna Krasnianski,Walter J. Schulz-Schaeffer,Kai Kallenberg,Bettina Meissner,Donald A. Collie,Sigrun Roeber,M. Bartl,Uta Heinemann,Daniela Varges,Hans A. Kretzschmar,Inga Zerr +10 more
TL;DR: Prolonged disease duration, early and prominent psychiatric symptoms, absence of typical EEG, thalamic hyperintensities on MRI and relatively low 14-3-3 protein sensitivity may be suspicious for variant CJD.