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José Pimentel

Researcher at University of Lisbon

Publications -  59
Citations -  4303

José Pimentel is an academic researcher from University of Lisbon. The author has contributed to research in topics: Epilepsy surgery & Epilepsy. The author has an hindex of 20, co-authored 55 publications receiving 3227 citations. Previous affiliations of José Pimentel include Instituto de Medicina Molecular.

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Journal ArticleDOI

Intertumoral Heterogeneity within Medulloblastoma Subgroups

Florence M.G. Cavalli, +101 more
- 12 Jun 2017 - 
TL;DR: Similarity network fusion (SNF) applied to genome-wide DNA methylation and gene expression data across 763 primary samples identifies very homogeneous clusters of patients, supporting the presence of medulloblastoma subtypes.
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Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.

Ingmar Blümcke, +74 more
TL;DR: In patients with drug‐resistant focal epilepsy requiring surgery, hippocampal sclerosis was the most common histopathological diagnosis among adults, and focal cortical dysplasia was the second most common lesion in both groups.
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Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

TL;DR: Subgroup-specific differences in the location and timing of recurrence across medulloblastoma subgroups have potential treatment ramifications and intensified local (posterior fossa) therapy should be tested in the initial treatment of patients with SHH tumours.
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Divergent clonal selection dominates medulloblastoma at recurrence

A. Sorana Morrissy, +141 more
- 21 Jan 2016 - 
TL;DR: Targeted therapy is unlikely to be effective in the absence of the target, therefore the results offer a simple, proximal, and remediable explanation for the failure of prior clinical trials of targeted therapy.