D
David A. Williams
Researcher at Boston Children's Hospital
Publications - 659
Citations - 46347
David A. Williams is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 106, co-authored 633 publications receiving 42058 citations. Previous affiliations of David A. Williams include Columbia University Medical Center & University of Cincinnati.
Papers
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Journal ArticleDOI
Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor
Krisztina M. Zsebo,David A. Williams,Edwin N. Geissler,Virginia C. Broudy,Francis Hall Martin,Harry L. Atkins,Rou Yin Hsu,Neal C. Birkett,Kenneth H. Okino,Murdock Douglas C,Frederick W. Jacobsen,Keith Langley,Kent A. Smith,Takashi Takeish,Bruce M. Cattanach,Stephen J. Galli,Sidney Vaughn Suggs +16 more
TL;DR: In vivo administration of SCF can reverse the macrocytic anemia and locally repair the mast cell deficiency of Sl/Sld mice and provide biological and physical evidence that SCF is a ligand for the c-kit receptor.
Update on Empirically Validated Therapies, II
Dianne L. Chambless,Mary J. Baker,Donald H. Baucom,Larry E. Beutler,Karen S. Calhoun,Paul Crits-Christoph,Anthony D. Daiuto,Robert J. DeRubeis,Jerusha Detweiler,David A. F. Haaga,Suzanne Bennett Johnson,Susan M. McCurry,Kim T. Mueser,Kenneth S. Pope,William C. Sanderson,Varda Shoham,Timothy R. Stickle,David A. Williams +17 more
Book
Foye's Principles of Medicinal Chemistry
TL;DR: This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy.
Journal ArticleDOI
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
Jonathan D. Pollock,David A. Williams,David A. Williams,Mary A.C. Gifford,Ling Lin Li,Xunxiang Du,Jason Fisherman,Stuart H. Orkin,Stuart H. Orkin,Claire M. Doerschuk,Mary C. Dinauer +10 more
TL;DR: Gene targeting was used to generate mice with a null allele of the gene involved in X–linked CGD, which encodes the 91 kD subunit of the oxidase cytochrome b, and affected hemizygous male mice lacked phagocyte superoxide production and had an altered inflammatory response in thioglycollate peritonitis.
Journal ArticleDOI
Pain catastrophizing and neural responses to pain among persons with fibromyalgia
Richard H. Gracely,Michael E. Geisser,Thorsten Giesecke,Masilo A. B. Grant,Frank Petzke,David A. Williams,Daniel J. Clauw +6 more
TL;DR: The findings suggest that pain catastrophizing, independent of the influence of depression, is significantly associated with increased activity in brain areas related to anticipation of pain, attention to pain, and emotional aspects of pain.