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David D. McPherson
Researcher at University of Texas Health Science Center at Houston
Publications - 233
Citations - 6071
David D. McPherson is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Liposome & Ultrasound. The author has an hindex of 42, co-authored 214 publications receiving 5679 citations. Previous affiliations of David D. McPherson include University of Texas at Austin & United States Department of Veterans Affairs.
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Journal ArticleDOI
Treadmill Exercise and Resistance Training in Patients With Peripheral Arterial Disease With and Without Intermittent Claudication: A Randomized Controlled Trial
Mary M. McDermott,Philip A. Ades,Jack M. Guralnik,Alan R. Dyer,Luigi Ferrucci,Kiang Liu,Miriam E. Nelson,Donald M. Lloyd-Jones,Linda Van Horn,Daniel B. Garside,Melina R. Kibbe,Kathryn Domanchuk,James H. Stein,Yihua Liao,Huimin Tao,David Green,William H. Pearce,Joseph R. Schneider,David D. McPherson,Susan T. Laing,Walter J. McCarthy,Adhir Shroff,Michael H. Criqui +22 more
TL;DR: Supervised treadmill training improved 6-minute walk performance, treadmill walking performance, brachial artery flow-mediated dilation, and quality of life but did not improve the short physical performance battery scores of PAD participants with and without intermittent claudication.
Journal ArticleDOI
In vivo targeting of acoustically reflective liposomes for intravascular and transvascular ultrasonic enhancement.
Sasha M. Demos,Hayat Alkan-Onyuksel,Bonnie J. Kane,Kishin Ramani,Ashwin Nagaraj,Rodney Greene,Melvin E. Klegerman,David D. McPherson +7 more
TL;DR: The data demonstrate that this novel acoustic agent can provide varying targeting with different antibodies with retention of intravascular and transvascular acoustic properties.
Journal ArticleDOI
Intravascular ultrasound molecular imaging of atheroma components in vivo
Andrew J. Hamilton,Shaoling Huang,Drew Warnick,Mark G. Rabbat,Bonnie J. Kane,Ashwin Nagaraj,Melvin E. Klegerman,David D. McPherson +7 more
TL;DR: It was shown that ELIPs specifically enhance endothelial injury/atheroma components, which allows better characterization of the type and extent of active atheroma components and may allow more directed therapy.
Journal ArticleDOI
Development of Inherently Echogenic Liposomes as an Ultrasonic Contrast Agent
Hayat Alkan-Onyuksel,Sasha M. Demos,Gregory M. Lanza,Michael J. Vonesh,Melvin E. Klegerman,Bonnie J. Kane,Jer R. Kuszak,David D. McPherson +7 more
TL;DR: This study developed acoustically reflective liposomes, which are suitable for antibody conjugation, without using gas or any other agent entrapment, and can be used for ultrasonic image enhancement and/or treatment of targeted pathologic sites.
Journal ArticleDOI
Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes.
Susan D. Tiukinhoy-Laing,Shaoling Huang,Melvin E. Klegerman,Christy K. Holland,David D. McPherson +4 more
TL;DR: This study demonstrated entrapment of tPA into ELIP with effective clot lysis and drug release using ultrasound, and demonstrated tPA-loaded ELIP has potential for specific highlighting of clots to confirm agent delivery and help focus ultrasound therapy for targeted ultrasound-facilitated thrombolysis.