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David E. Shaw

Researcher at D. E. Shaw Research

Publications -  326
Citations -  50142

David E. Shaw is an academic researcher from D. E. Shaw Research. The author has contributed to research in topics: Massively parallel & G protein-coupled receptor. The author has an hindex of 88, co-authored 298 publications receiving 42616 citations. Previous affiliations of David E. Shaw include Protein Sciences & Genentech.

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Patent

Electronic mail system for displaying advertisement at local computer received from remote system while the local computer is off-line the remote system

TL;DR: In this paper, the authors present a system for providing scheduled messages to a remote user in a batch oriented system, where a user creates and/or reads electronic mail locally and a message is displayed to the user on a portion of the local monitor, the message preferably changing in accordance with local display schedule and stored on a local storage device.
Journal ArticleDOI

Mechanism of Voltage Gating in Potassium Channels

TL;DR: A mechanistic model for the sodium/potassium/calcium voltage-gated ion channel superfamily is proposed that reconciles apparently conflicting experimental data.
Journal ArticleDOI

Activation mechanism of the β2-adrenergic receptor

TL;DR: An activation mechanism for the β2-adrenergic receptor, a prototypical GPCR, is proposed based on atomic-level simulations in which an agonist-bound receptor transitions spontaneously from the active to the inactive crystallographically observed conformation.
Patent

Electronic mail system with advertising

TL;DR: In this article, the authors present a system for providing scheduled messages to a remote user in a batch oriented system, where a user creates and/or reads electronic mail locally and a message is displayed to the user on a portion of the local monitor, the message preferably changing in accordance with local display schedule and stored on a local storage device.