D
David Hau
Researcher at University of Alberta
Publications - 10
Citations - 6256
David Hau is an academic researcher from University of Alberta. The author has contributed to research in topics: Human Metabolome Database & Metabolome. The author has an hindex of 7, co-authored 10 publications receiving 5516 citations. Previous affiliations of David Hau include National Institute for Nanotechnology.
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Journal ArticleDOI
HMDB: The human metabolome database
David S. Wishart,Dan Tzur,Craig Knox,Roman Eisner,An Chi Guo,Nelson Young,Dean Cheng,Kevin Jewell,David Arndt,Summit Sawhney,Chris Fung,Lisa Nikolai,Michael J. Lewis,Marie-Aude Coutouly,Ian D. Forsythe,Peter Tang,Savita Shrivastava,Kevin Jeroncic,Paul Stothard,Godwin Amegbey,David Block,David Hau,James Wagner,Jessica Miniaci,Melisa Clements,Mulu Gebremedhin,Natalie Guo,Ying Wen Zhang,Gavin E. Duggan,Glen D. MacInnis,Alim M. Weljie,Reza Dowlatabadi,Fiona Bamforth,Derrick L. J. Clive,Russell Greiner,Liang Li,Thomas J. Marrie,Brian D. Sykes,Hans J. Vogel,Lori M.M. Querengesser +39 more
TL;DR: The Human Metabolome Database is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community.
Journal ArticleDOI
HMDB: a knowledgebase for the human metabolome
David S. Wishart,Craig Knox,An Chi Guo,Roman Eisner,Nelson Young,Bijaya Gautam,David Hau,Nick Psychogios,Edison Dong,Souhaila Bouatra,Rupasri Mandal,Igor Sinelnikov,Jianguo Xia,Leslie Jia,Joseph A. Cruz,Emilia L. Lim,Constance A. Sobsey,Savita Shrivastava,Paul Huang,Philip Liu,Lydia Fang,Jun Peng,Ryan Fradette,Dean Cheng,Dan Tzur,Melisa Clements,Avalyn Lewis,Andrea De Souza,Azaret Zuniga,Margot Dawe,Yeping Xiong,Derrick L. J. Clive,Russell Greiner,Alsu Nazyrova,Rustem Shaykhutdinov,Liang Li,Hans J. Vogel,Ian J. Forsythe +37 more
TL;DR: The most recent release of HMDB has been significantly expanded and enhanced over the previous release, with the number of fully annotated metabolite entries growing from 2180 to more than 6800, a 300% increase.
Journal ArticleDOI
The Human Serum Metabolome
Nikolaos Psychogios,David Hau,Jun Peng,An Chi Guo,Rupasri Mandal,Souhaila Bouatra,Igor Sinelnikov,Ramanarayan Krishnamurthy,Roman Eisner,Bijaya Gautam,Nelson Young,Jianguo Xia,Craig Knox,Edison Dong,Paul Huang,Zsuzsanna Hollander,Theresa L. Pedersen,Steven R. Smith,Fiona Bamforth,Russell Greiner,Bruce M. McManus,John W. Newman,Theodore L. Goodfriend,David S. Wishart,David S. Wishart +24 more
TL;DR: This work has combined targeted and non-targeted NMR, GC-MS and LC-MS methods with computer-aided literature mining to identify and quantify a comprehensive, if not absolutely complete, set of metabolites commonly detected and quantified (with today's technology) in the human serum metabolome.
Journal ArticleDOI
SMPDB: The Small Molecule Pathway Database.
Alex Frolkis,Craig Knox,Emilia L. Lim,Timothy Jewison,Vivian Law,David Hau,Phillip Liu,Bijaya Gautam,Son Ly,An Chi Guo,Jianguo Xia,Yongjie Liang,Savita Shrivastava,David S. Wishart +13 more
TL;DR: The Small Molecule Pathway Database (SMPDB) is an interactive, visual database containing more than 350 small-molecule pathways found in humans, designed specifically to support pathway elucidation and pathway discovery in clinical metabolomics, transcriptomics, proteomics and systems biology.
Journal ArticleDOI
Learning to predict cancer-associated skeletal muscle wasting from 1H-NMR profiles of urinary metabolites
Roman Eisner,Cynthia Stretch,Thomas Eastman,Jianguo Xia,David Hau,Sambasivarao Damaraju,Russell Greiner,David S. Wishart,Vickie E. Baracos +8 more
TL;DR: 1H-NMR analysis of a single random urine sample may be a fast, cheap, safe and inexpensive tool to screen and monitor muscle loss, and that useful classifiers for predicting related metabolic conditions are possible with the methodology presented.