D
David J. Benz
Researcher at University of Arizona
Publications - 4
Citations - 1004
David J. Benz is an academic researcher from University of Arizona. The author has contributed to research in topics: Estrogen & Osteoblast. The author has an hindex of 3, co-authored 4 publications receiving 998 citations.
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Journal ArticleDOI
Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells
Barry S. Komm,Christopher M. Terpening,David J. Benz,Kimberlie A. Graeme,Alfred Gallegos,Murray Korc,Geoffrey L. Greene,Bert W. O'Malley,Mark R. Haussler +8 more
TL;DR: Estradiol can act directly on osteoblasts by a receptor-mediated mechanism and thereby modulate the extracellular matrix and other proteins involved in the maintenance of skeletal mineralization and remodeling.
Journal ArticleDOI
High-Affinity Androgen Binding and Androgenic Regulation of α1(I)-Procollagen and Transforming Growth Factor-β Steady State Messenger Ribonucleic Acid Levels in Human Osteoblast-Like Osteosarcoma Cells*
TL;DR: It is now evident that these osteoblast-like osteosarcoma cells also express high affinity androgen binding sites and can respond biologically to androgens.
Journal ArticleDOI
Estrogen binding and estrogenic responses in normal human osteoblast‐like cells
TL;DR: Previous data obtained in osteoblast‐like osteosarcoma cells are extended to indicate that a normal osteoblastic cell line is a target for the action of estrogen.