D
David Kane
Researcher at Trinity College, Dublin
Publications - 117
Citations - 8090
David Kane is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Psoriatic arthritis & Arthritis. The author has an hindex of 45, co-authored 108 publications receiving 7370 citations. Previous affiliations of David Kane include Boston Children's Hospital & Newcastle University.
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Correction: Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
John Bowes,Ashley Budu-Aggrey,Ulrike Hüffmeier,Steffen Uebe,Kathryn J. A. Steel,Harry L. Hébert,Chris Wallace,Jonathon Massey,Ian N. Bruce,James Bluett,Marie Feletar,Ann W. Morgan,Helena Marzo-Ortega,Gary Donohoe,Derek W. Morris,Philip S. Helliwell,Anthony W. Ryan,David Kane,Richard B. Warren,Eleanor Korendowych,Gerd-Marie Alenius,Emiliano Giardina,Jonathan Packham,Ross McManus,Oliver FitzGerald,Neil McHugh,Matthew A. Brown,Pauline Ho,Frank Behrens,Harald Burkhardt,André Reis,Anne Barton +31 more
TL;DR: This work presents a novel and scalable approach to genome-based approaches that combines cell reprograming, nanofiltration, and ‘spatially aggregating’ techniques that allow for real-time assessment of the impact of environmental factors on gene expression and disease progression.
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Ultrasonography of entheseal insertions in the lower limb in spondyloarthropathy
TL;DR: US is better than clinical examination in the detection of entheseal abnormality of the lower limb in patients with spondyloarthropathy, and a quantitative US score of lower limb enthesitis is proposed but further studies are required to validate it in SpA.
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A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience
TL;DR: This study confirms that PsA is a chronic, progressive disease in the majority of patients despite clinical improvement with current DMARD treatment, PsA results in radiological damage in up to 47% of patients at a median interval of 2 yr.
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Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis
Dirk Foell,David Kane,Barry Bresnihan,Thomas J. Vogl,Wolfgang Nacken,Clemens Sorg,Oliver FitzGerald,Johannes Roth +7 more
TL;DR: High serum concentrations of S100A12 in patients with active arthritis compared with healthy controls or patients in remission point to its usefulness as a serum marker, especially in PsA.
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Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce - Part 1: definition and development of a standardised, consensus-based scoring system.
Maria Antonietta D'Agostino,Lene Terslev,Philippe Aegerter,Marina Backhaus,Peter V. Balint,George A W Bruyn,Emilio Filippucci,Walter Grassi,Annamaria Iagnocco,Sandrine Jousse-Joulin,David Kane,Esperanza Naredo,Wolfgang A. Schmidt,Marcin Szkudlarek,Philip G. Conaghan,Richard J. Wakefield +15 more
TL;DR: A multistep consensus-based process has produced a standardised US definition and quantification system for RA synovitis including combined and individual SH and PD components.