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David L. Molfese
Researcher at Baylor College of Medicine
Publications - 21
Citations - 3278
David L. Molfese is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Histone & Resting state fMRI. The author has an hindex of 14, co-authored 21 publications receiving 3024 citations. Previous affiliations of David L. Molfese include Michael E. DeBakey Veterans Affairs Medical Center in Houston & University of Houston.
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Journal ArticleDOI
Regulation of histone acetylation during memory formation in the hippocampus.
Jonathan M. Levenson,Kenneth J. O’Riordan,Karen D. Brown,Mimi A. Trinh,David L. Molfese,J. David Sweatt +5 more
TL;DR: Results indicate that histone-associated heterochromatin undergoes changes in structure during the formation of long term memory, which enhances a cellular process thought to underlie longterm memory formation, hippocampal long term potentiation, and memory formation itself.
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Anterior Cingulate Cortex and Response Conflict: Effects of Frequency, Inhibition and Errors
TL;DR: The results are consistent with the hypothesis that the ACC serves as a generic detector of processing conflict arising when low-frequency responses must be executed, but also leave open the possibility that further functional specialization may occur within ACC subregions.
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Histone Methylation Regulates Memory Formation
Swati Gupta,Se Young Kim,S. Artis,David L. Molfese,Axel Schumacher,J. D. Sweatt,R. E. Paylor,Farah D. Lubin +7 more
TL;DR: The finding that trimethylation of histone H3 at lysine 4 (H3K4), an active mark for transcription, is upregulated in hippocampus 1 h following contextual fear conditioning, demonstrates that histone methylation is actively regulated in the hippocampus and facilitates long-term memory formation.
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The role of the habenula in drug addiction.
TL;DR: The habenula is a critical crossroad that influences the brain’s response to pain, stress, anxiety, sleep, and reward, and is linked to depression, schizophrenia, and the effects of drugs of abuse.
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The medial habenula: still neglected
TL;DR: While the lateral habenula (LHb) has been extensively studied, the anatomically and histochemically distinct medial habenulas (MHb) remains largely understudied.