D
David Luesley
Researcher at University of Birmingham
Publications - 175
Citations - 5236
David Luesley is an academic researcher from University of Birmingham. The author has contributed to research in topics: Colposcopy & Cervical cancer. The author has an hindex of 33, co-authored 175 publications receiving 4774 citations. Previous affiliations of David Luesley include Birmingham City Hospital.
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Primary chemotherapy versus primary surgery for newly diagnosed advanced ovarian cancer (CHORUS): an open-label, randomised, controlled, non-inferiority trial
Sean Kehoe,Jane Hook,Matthew Nankivell,Gordon C Jayson,Henry C Kitchener,Tito Lopes,David Luesley,Timothy J. Perren,Selina Bannoo,Monica Mascarenhas,Stephen Dobbs,Sharadah Essapen,Jeremy Twigg,Jonathan Herod,Glenn McCluggage,Mahesh K.B. Parmar,Ann Marie Swart,Ann Marie Swart +17 more
TL;DR: In women with stage III or IV ovarian cancer, survival with primary chemotherapy is non-inferior to primary surgery, and giving primary chemotherapy before surgery is an acceptable standard of care for women with advanced ovarian cancer.
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Management of women who test positive for high-risk types of human papillomavirus: The HART study
Jack Cuzick,Anne Szarewski,Heather Cubie,G Hulman,Henry C Kitchener,David Luesley,Euphemia McGoogan,Usha Menon,George Terry,Robert Edwards,Claire Brooks,Mina Desai,C Gie,Linda Lee Ho,Ian Jacobs,C Pickles,Peter Sasieni +16 more
TL;DR: Comparison of the detection rate and positive predictive values of HPV assay with cytology and the best management strategy for HPV-positive women found HPV testing was more sensitive than borderline or worse cytology but less specific for detecting CIN2+.
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Regression, relapse, and live birth rates with fertility-sparing therapy for endometrial cancer and atypical complex endometrial hyperplasia: a systematic review and metaanalysis
Ioannis D. Gallos,Jason Yap,Madhurima Rajkhowa,David Luesley,Aravinthan Coomarasamy,Janesh K. Gupta +5 more
TL;DR: Fertility-sparing treatment of EC and ACH is feasible and selected women can satisfy their reproductive wishes and a meta-regression to explore for heterogeneity is explored.
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Loop diathermy excision of the cervical transformation zone in patients with abnormal cervical smears.
David Luesley,J. Cullimore,Charles W.E. Redman,F. G. Lawton,J. M. Emens,T. P. Rollason,D. R. Williams,E. J. Buxton +7 more
TL;DR: Loop diathermy excision is an effective treatment with low morbidity and is an appropriate modality for patients with abnormal cervical smears.
Journal ArticleDOI
Colposcopically directed punch biopsy: a potentially misleading investigation.
TL;DR: To determine the relation between the histology of an initial colposcopically directed punch biopsy and a subsequent diathermy loop excision biopsy of the transformation zone, and the effect of lesion size on this relation.