Showing papers in "American Journal of Obstetrics and Gynecology in 2012"
Lucile Packard Children's Hospital1, University of California, San Diego2, Oregon Health & Science University3, Cedars-Sinai Medical Center4, Medical College of Wisconsin5, University of Tennessee Health Science Center6, University of California, San Francisco7, Sahlgrenska University Hospital8, Leiden University Medical Center9
TL;DR: Ch Chromosome-selective sequencing of cell-free DNA and application of an individualized risk algorithm is effective in the detection of fetal T21 and T18.
539 citations
National Institutes of Health1, University of Cambridge2, University of Copenhagen3, Copenhagen University Hospital4, University of Kentucky5, University of São Paulo6, Medical University of Vienna7, University of Pretoria8, Government Medical College, Thiruvananthapuram9, University of Liverpool10, Wayne State University11
TL;DR: Vaginal progesterone administration to asymptomatic women with a sonographic short cervix in the midtrimester reduces the risk of preterm birth and neonatal morbidity and mortality.
510 citations
TL;DR: In this paper, a systematic review of the literature was conducted to estimate the number of women who seek treatment for symptomatic fibroid tumors annually, the costs of medical and surgical treatment, the amount of work time lost, and obstetric complications that are attributable to fibroid tumor.
510 citations
TL;DR: The review resulted in several conclusions: the diagnosis of placenta accreta and cesarean scar pregnancy is difficult; transvaginal ultrasound seems to be the best diagnostic tool to establish the diagnosis and local methotrexate- and hysteroscopic-directed procedures had the lowest complication rates.
476 citations
TL;DR: Digital analysis of selected regions and FORTE enable accurate, scalable noninvasive fetal aneuploidy detection and produce an individualized trisomy risk score for each subject.
448 citations
TL;DR: The sFlt-1/PlGF ratio allows the identification of women at risk for imminent delivery and is a reliable tool to discriminate between different types of pregnancy-related hypertensive disorders.
363 citations
TL;DR: Noninvasive prenatal testing for fetal trisomy in a routinely screened first-trimester pregnancy population identified trisomies 21 and 18 with a false-positive rate of 0.1%.
332 citations
TL;DR: The risks for influenza-associated complications among pregnant women and infants <6 months old are reviewed and influenza vaccination during pregnancy is shown to decrease the risk of influenza and its complications.
322 citations
TL;DR: In this study, chromosome-selective sequencing of cell-free DNA separated all cases of trisomy 21 and 98% oftrisomy 18 from euploid pregnancies.
318 citations
TL;DR: Combined intramuscular and intragestational methotrexate injection treatment was successful in treating 19 of the 26 patients suspected to have cesarean scar pregnancy.
316 citations
TL;DR: Fertility-sparing treatment of EC and ACH is feasible and selected women can satisfy their reproductive wishes and a meta-regression to explore for heterogeneity is explored.
TL;DR: It is indicated that, among high-risk pregnancies with suspected IUGR, the use of umbilical arterial Doppler assessment significantly decreases the likelihood of labor induction, cesarean delivery, and perinatal deaths.
TL;DR: CSs that are potentially medically unjustified appear to command a disproportionate share of global economic resources.
TL;DR: V vulvodynia is common, although rarely diagnosed, and remains high among sexually active women of any age, and among sexuallyActive women, the prevalence was similar at all ages.
TL;DR: The objective of this review is to increase awareness and to provide a stepwise approach toward the diagnosis and management of women with persistent and/or new-onset hypertension-preeclampsia postpartum period.
TL;DR: Primary and secondary chronic hypertension were both strongly associated with adverse pregnancy outcomes and accounted for a substantial fraction of maternal morbidity.
TL;DR: In many countries, selenium dietary intake falls below the recommended nutrient intakes and is inadequate to support maximal expression of the selenoenzymes.
TL;DR: Both cytologic abnormalities and hrHPV positivity declined with increasing age, and the adjusted prevalence of cervical intraepithelial neoplasia grade 2 (CIN2) or greater in women aged 25-34 years was 2.3%, decreasing to 1.5% among older women.
TL;DR: IPI placement in adolescents has excellent continuation 1 year after delivery; rapid repeat pregnancy is significantly decreased compared with control participants.
TL;DR: Pregnant women with OSA are at increased risk for having LBW, preterm, and SGA infants, CS, and preeclampsia, compared with pregnant women without OSA.
TL;DR: A comprehensive classification system for preterm birth requires expanded gestational boundaries that recognize the early origins of preterm parturition and emphasize fetal maturity over fetal age.
TL;DR: A classification that is based on clinical phenotypes that are defined by ≥ 1 characteristics of the mother, the fetus, the placenta, the signs of parturition, and the pathway to delivery is proposed.
TL;DR: Adenomyosis appears to consist of 3 distinct subtypes of different causes and an additional subtype of indeterminate cause.
TL;DR: A non-NICHD measure of deceleration frequency and severity in the second stage performed superior to 4 NICHD EFM features for predicting fetal acidemia.
TL;DR: Fetal cardiovascular programming occurs in SGA, regardless of Doppler and weight centile, and these findings challenge the concept of constitutionally small and warrant further investigation to identify predictors of cardiovascular outcome in S GA.
TL;DR: There is an increase in the risk of IUFD in SGA fetuses compared to non-SGA Fetuses at all gestational ages with the greatest risk demonstrated in the lowest percentile cohort evaluated.
TL;DR: Issues related to measurement of gestational age, clinical vs etiologic phenotypes, inclusion vs exclusion of multifetal and stillborn infants, and separation vs combination of pathways to preterm birth are reviewed.
TL;DR: This study suggests that certain occupational exposures common to nurses are related to risks of spontaneous abortion.
TL;DR: First-trimester use of topiramate monotherapy in pregnancy and cleft lip with or without cleft palate in the offspring may be associated with CL/P.
Northwestern University1, George Washington University2, National Institutes of Health3, Ohio State University4, University of Texas Medical Branch5, Case Western Reserve University6, University of Alabama at Birmingham7, Brown University8, Wayne State University9, Columbia University10, University of Texas at Dallas11, University of Texas Health Science Center at Houston12, University of Utah13, Oregon Health & Science University14, University of North Carolina at Chapel Hill15, University of Pittsburgh16, Medical University of South Carolina17
TL;DR: The frequency of PTB did not differ between the 17-OHP and placebo groups (25.1% vs 24.2%; relative risk, 1.03; 95% confidence interval, 0.79•1.35) as discussed by the authors.