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David M. Armstrong

Researcher at Lankenau Institute for Medical Research

Publications -  78
Citations -  7393

David M. Armstrong is an academic researcher from Lankenau Institute for Medical Research. The author has contributed to research in topics: Choline acetyltransferase & Cholinergic neuron. The author has an hindex of 45, co-authored 78 publications receiving 7266 citations. Previous affiliations of David M. Armstrong include Albert Einstein College of Medicine & Cornell University.

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Distribution of cholinergic neurons in rat brain: Demonstrated by the immunocytochemical localization of choline acetyltransferase

TL;DR: The correspondence of the distribution of ChAT‐labeled neurons identified by the methods to earlier immunocytochemical and acetylcholinesterase histochemical studies and to connectional studies of these groups argues for the specificity of the ChAT antibody used.
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A comparison of the distribution of central cholinergic neurons as demonstrated by acetylcholinesterase pharmacohistochemistry and choline acetyltransferase immunohistochemistry

TL;DR: Close correspondence was observed in the distribution of labeled neurons obtained by the two histochemical procedures in the midbrain and pontine tegmentum, including the laterodorsal tegmental nucleus, some areas in the caudal pontine and bulbar reticular formation, and the central gray of the closed medulla oblongata.
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Distribution of dopamine-, noradrenaline-, and adrenaline-containing cell bodies in the rat medulla oblongata: demonstrated by the immunocytochemical localization of catecholamine biosynthetic enzymes.

TL;DR: The detection of perikarya which show immunoreactivity for TH, used in the biosynthesis of dopamine, noradrenaline, and adrenaline, but not DBH, which converts dopamine to norad Renaline, suggests the existence of dopamine‐synthesiz‐ing neurons in the medulla.
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NADPH-diaphorase: A selective histochemical marker for the cholinergic neurons of the pontine reticular formation☆

TL;DR: NADPH-diaphorase histochemistry provides a simple, reliable method to selectively stain the cholinergic neurons of the brainstem reticular formation and should therefore be of great value in morphological studies of this cholin allergic cell group.
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Morphological response of axotomized septal neurons to nerve growth factor.

TL;DR: Qualitative morphometric techniques evaluated the response of axotomized septal neurons to a constant infusion of nerve growth factor (NGF) and saved neurons had the same parameters as the undamaged ChAT‐IR neurons when examined in either 40‐μm‐ or 1‐ μm‐thick sections.