Silvio Varon

TL;DR: Data suggest that BDNF protein produced in adult CNS neurons is polarized primarily along axonal processes and is preferentially stored in terminals within the innervation target.

TL;DR: It is reported here that NGF treatment significantly reduces both the total neuronal and cholinergic neuronal death found 2 weeks after fimbria fornix transection; there was a sparing of 50% of the neurons in the MS and essentially 100% of those in the VDB that otherwise would have died.

TL;DR: Continuous intracerebral infusion of NGF over a period of four weeks can partly reverse the cholinergic cell body atrophy and improve retention of a spatial memory task in behaviourally impaired aged rats.

TL;DR: Tissue culture methods are used to examine the relative ability of various extracellular matrix components to elicit neurite outgrowth from dissociated chick embryo parasympathetic neurons in serum-free monolayer culture and conclude that laminin and PNPF-1 are distinct macromolecules capable of expressing their neurite-promoting activities even when presented in nanogram amounts.

TL;DR: A revision is proposed in which the four fundamental zones are termed the ventricular, subventricular, intermediate, and marginal zones, each defined according to the form, behavior, and fate of its constituent cells.