D
David Russell
Researcher at McMaster University
Publications - 6
Citations - 1406
David Russell is an academic researcher from McMaster University. The author has contributed to research in topics: Transplantation & Renal function. The author has an hindex of 5, co-authored 5 publications receiving 1386 citations.
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Journal ArticleDOI
A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
Paul Keown,Pekka Häyry,Peter J. Morris,Calvin R. Stiller,Christopher M. Barker,Lisa Carr,David Landsberg,Ian R. Hardie,Russell J. Rigby,Helena Isoniemi,Derek W. R. Gray,Philip Belitsky,Allan McDonald,Tim Mathew,A. Clarkson,L. Barratt,B. Buchholz,Rowan Walker,Günther Kirste,Norman Muirhead,David J. Tiller,Geoff Duggin,Philip F. Halloran,Pierre Daloze,Gilles St. Louis,David Russell,David Ludwin,P. Vialtel,U. Binswanger,J. A C Buckels,Jean Louis Touraine,David P. Hickey,Giuseppe Remuzzi,Giuseppe Locatelli,F. T. Lam,Ed Tapper +35 more
TL;DR: MMF is associated with a significantly lower rate of treatment failure compared with AZA during the first 6 months after renal transplantation and produces a clinically important reduction in the incidence, severity, and treatment of acute graft rejection.
Journal ArticleDOI
A randomized, prospective multicenter pharmacoepidemiologic study of cyclosporine microemulsion in stable renal graft recipients. Report of the Canadian Neoral Renal Transplantation Study Group.
Paul Keown,David Landsberg,P. Halloran,Ahmed Shoker,David N. Rush,John Jeffery,David Russell,Calvin R. Stiller,Norman Muirhead,Edward S. Cole,L. C. Paul,Jeffrey S. Zaltzman,Rolf Loertscher,Pierre Daloze,Raymond Dandavino,Anne Boucher,Paul Handa,Joseph Lawen,Phillip Belitsky,Patrick S. Parfrey +19 more
TL;DR: MeCsA appears to be a safe and effective therapy in stable renal transplant patients and provides superior and more consistent absorption of cyclosporine when compared with ConCsA, a prospective, randomized, concentration-controlled, pharmacoepidemiologic study.
Journal ArticleDOI
A pilot study of steroid-free immunosuppression in the prevention of acute rejection in renal allograft recipients.
Edward H. Cole,David Landsberg,David Russell,Jeffrey S. Zaltzman,Bryce A. Kiberd,Ciro Caravaggio,Arthur R. Vasquez,Philip F. Halloran +7 more
TL;DR: It is believed steroid avoidance with this immunosuppressive regimen would permit transplantation without steroids, and the basis of these positive results merits further study.
Journal ArticleDOI
Safety and tolerability of cyclosporine and cyclosporine microemulsion during 18 months of follow-up in stable renal transplant recipients: a report of the Canadian Neoral Renal Study Group.
Edward Cole,Paul Keown,David Landsberg,P. Halloran,Ahmed Shoker,David N. Rush,John Jeffrey,David Russell,Calvin R. Stiller,Norman Muirhead,L. C. Paul,Jeffrey S. Zaltzman,Rolf Loertscher,Pierre Daloze,Raymond Dandavino,Anne Boucher,Paul Handa,Joseph Lawen,Phillip Belitsky,Patrick S. Parfrey,Annette Tan,Lisa Hendricks +21 more
TL;DR: Renal function over 18 months was not adversely affected by the increased drug exposure with CsA-ME, although there was a transient increase in nephrotoxicity.