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Giuseppe Locatelli
Publications - 18
Citations - 1673
Giuseppe Locatelli is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 6 publications receiving 1601 citations.
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Journal ArticleDOI
A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
Paul Keown,Pekka Häyry,Peter J. Morris,Calvin R. Stiller,Christopher M. Barker,Lisa Carr,David Landsberg,Ian R. Hardie,Russell J. Rigby,Helena Isoniemi,Derek W. R. Gray,Philip Belitsky,Allan McDonald,Tim Mathew,A. Clarkson,L. Barratt,B. Buchholz,Rowan Walker,Günther Kirste,Norman Muirhead,David J. Tiller,Geoff Duggin,Philip F. Halloran,Pierre Daloze,Gilles St. Louis,David Russell,David Ludwin,P. Vialtel,U. Binswanger,J. A C Buckels,Jean Louis Touraine,David P. Hickey,Giuseppe Remuzzi,Giuseppe Locatelli,F. T. Lam,Ed Tapper +35 more
TL;DR: MMF is associated with a significantly lower rate of treatment failure compared with AZA during the first 6 months after renal transplantation and produces a clinically important reduction in the incidence, severity, and treatment of acute graft rejection.
Journal ArticleDOI
Long-Term Outcome of Renal Transplantation from Older Donors
Giuseppe Remuzzi,Paolo Cravedi,Annalisa Perna,Borislav D. Dimitrov,Marta Turturro,Giuseppe Locatelli,Paolo Rigotti,Nicola Baldan,M Beatini,Umberto Valente,Mario Scalamogna,Piero Ruggenenti +11 more
TL;DR: The long-term survival of single or dual kidney grafts from donors older than 60 years of age is excellent, provided that the grafts are evaluated histologically before implantation.
Journal ArticleDOI
Combined kidney and liver transplantation for familial haemolytic uraemic syndrome.
Giuseppe Remuzzi,Piero Ruggenenti,Daniela Codazzi,Marina Noris,Jessica Caprioli,Giuseppe Locatelli,Bruno Gridelli +6 more
TL;DR: A simultaneous kidney and liver transplantation in a 2-year-old child with HUS and a mutation in complement factor H to restore the defective factor H was successful, with no recurrence of the disease.
Journal ArticleDOI
Sequential monitoring of urine-soluble interleukin 2 receptor and interleukin 6 predicts acute rejection of human renal allografts before clinical or laboratory signs of renal dysfunction.
Federica Casiraghi,Piero Ruggenenti,Marina Noris,Giuseppe Locatelli,Norberto Perico,Annalisa Perna,Giuseppe Remuzzi +6 more
TL;DR: Sequential monitoring of urinary sIL-2R and IL-6 levels does allow very early diagnosis of rejection without invasive procedures and identifies the subgroup of patients at risk.
Journal ArticleDOI
Autoimmune neuroinflammation triggers mitochondrial oxidation in oligodendrocytes
Jasmin Steudler,Tim Ecott,Daniela Ivan,Elisa Bouillet,Sabrina Walthert,Kristina Berve,Tobias P. Dick,Britta Engelhardt,Giuseppe Locatelli +8 more
TL;DR: In this paper , the mitochondria of Oligodendrocytes (ODCs) were quantified using 2-photon imaging of the exposed spinal cord, showing significant mitochondrial oxidation in ODCs upon induction of the MS model experimental encephalomyelitis (EAE).