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Derek W. R. Gray
Researcher at John Radcliffe Hospital
Publications - 119
Citations - 5932
Derek W. R. Gray is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 36, co-authored 119 publications receiving 5790 citations. Previous affiliations of Derek W. R. Gray include University of Oxford & Churchill Hospital.
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Journal ArticleDOI
A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
Paul Keown,Pekka Häyry,Peter J. Morris,Calvin R. Stiller,Christopher M. Barker,Lisa Carr,David Landsberg,Ian R. Hardie,Russell J. Rigby,Helena Isoniemi,Derek W. R. Gray,Philip Belitsky,Allan McDonald,Tim Mathew,A. Clarkson,L. Barratt,B. Buchholz,Rowan Walker,Günther Kirste,Norman Muirhead,David J. Tiller,Geoff Duggin,Philip F. Halloran,Pierre Daloze,Gilles St. Louis,David Russell,David Ludwin,P. Vialtel,U. Binswanger,J. A C Buckels,Jean Louis Touraine,David P. Hickey,Giuseppe Remuzzi,Giuseppe Locatelli,F. T. Lam,Ed Tapper +35 more
TL;DR: MMF is associated with a significantly lower rate of treatment failure compared with AZA during the first 6 months after renal transplantation and produces a clinically important reduction in the incidence, severity, and treatment of acute graft rejection.
Journal ArticleDOI
Islet isolation assessment in man and large animals.
Camillo Ricordi,Camillo Ricordi,Derek W. R. Gray,Bernhard J. Hering,Dixon B. Kaufman,Garth L. Warnock,Norman M. Kneteman,S. P. Lake,Nicholas J.M. London,Carlo Socci,Rodolfo Alejandro,Y. Zeng,David W. Scharp,Giorgio Luciano Viviani,L. Falqui,Andreas G. Tzakis,Reinhard G. Bretzel,Konrad Federlin,Guido Pozza,Roger F.L. James,Ray V. Rajotte,Valerio Di Carlo,Peter J. Morris,David E.R. Sutherland,Thomas E. Starzl,Daniel H. Mintz,Paul E. Lacy +26 more
TL;DR: These general guidelines will be of assistance to standardize the assessment of islet isolations, making it possible to better interpret and compare procedures from different centers.
Journal ArticleDOI
HLA class II induction in human islet cells by interferon-gamma plus tumour necrosis factor or lymphotoxin.
Ricardo Pujol-Borrell,I Todd,M Doshi,G F Bottazzo,Robert Sutton,Derek W. R. Gray,G R Adolf,Marc Feldmann +7 more
TL;DR: It is reported here that IFN-γ in combination with either TNF or LT induces islet cell class II expression, which has important implications for the pathogenesis of type I diabetes and the understanding of the differential control of class IIexpression.
Journal ArticleDOI
Major effects of delayed graft function and cold ischaemia time on renal allograft survival
Isabel Quiroga,P. McShane,Dicken D. H. Koo,Derek W. R. Gray,Peter J. Friend,Susan V. Fuggle,Christopher R. Darby +6 more
TL;DR: The results of this analysis of well-matched transplant recipients show that CIT and DGF are the most important predictors of poor short and long-term graft survival.