D
David S. Dunn
Researcher at Murdoch University
Publications - 34
Citations - 1228
David S. Dunn is an academic researcher from Murdoch University. The author has contributed to research in topics: Human leukocyte antigen & Gene. The author has an hindex of 17, co-authored 34 publications receiving 1154 citations. Previous affiliations of David S. Dunn include University of Western Australia.
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Journal ArticleDOI
IL28B, HLA-C and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a european cohort: A cross-sectional study
Vijayaprakash Suppiah,Silvana Gaudieri,Nicola J. Armstrong,Kate S. O'Connor,Thomas Berg,Martin Weltman,Maria Lorena Abate,Ulrich Spengler,Margaret F. Bassendine,Gregory J. Dore,Gregory J. Dore,William L. Irving,Elizabeth E. Powell,Elizabeth E. Powell,Margaret Hellard,Stephen M. Riordan,Gail V. Matthews,Gail V. Matthews,David Sheridan,Jacob Nattermann,Antonina Smedile,Tobias Müller,Emma Hammond,David S. Dunn,Francesco Negro,Pierre-Yves Bochud,Simon Mallal,Golo Ahlenstiel,Graeme J. Stewart,Jacob George,David R. Booth +30 more
TL;DR: Genotyping hepatitis C patients for the IL28B, HLA-C, and KIR genes improves the ability to predict whether or not patients will respond to antiviral treatment.
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Ten years of bacterial genome sequencing: comparative-genomics-based discoveries
Tim T. Binnewies,Yair Motro,Peter Fischer Hallin,Ole Lund,David S. Dunn,Tom La,David J. Hampson,Matthew I. Bellgard,Trudy M. Wassenaar,David W. Ussery +9 more
TL;DR: It has become clear that a genome sequence represents more than just a collection of gene sequences for an organism and that information concerning the environment and growth conditions for the organism are important for interpretation of the genomic data.
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Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine.
Matthew I. Bellgard,Phatthanaphong Wanchanthuek,Phatthanaphong Wanchanthuek,Tom La,K. Ryan,Paula Moolhuijzen,Zayed Albertyn,Babak Shaban,Yair Motro,David S. Dunn,D. Schibeci,Adam Hunter,Roberto A. Barrero,Nyree D. Phillips,David J. Hampson +14 more
TL;DR: The genome sequence of B. hyodysenteriae strain WA1 was determined, making it the first representative of the genus Brachyspira to be sequenced, and the seventeenth spirochete genome to be reported.
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Development of a multilocus sequence typing scheme for intestinal spirochaetes within the genus Brachyspira.
Therese Råsbäck,Karl-Erik Johansson,Désirée S. Jansson,Claes Fellström,Mohammad Yousef Alikhani,Tom La,David S. Dunn,David J. Hampson +7 more
TL;DR: A population snapshot showed a close phylogenetic relationship amongst the porcine isolates from the same geographical regions, and indicated a close evolutionary relationship between isolates recovered from pigs and mallards.
Journal ArticleDOI
HLA Class I restricted CD8+ and Class II restricted CD4+ T cells are implicated in the pathogenesis of nevirapine hypersensitivity.
Niamh M. Keane,Rebecca Pavlos,Elizabeth McKinnon,Andrew Lucas,Craig M. Rive,Christopher C Blyth,David S. Dunn,Michaela Lucas,Simon Mallal,Elizabeth J. Phillips +9 more
TL;DR: The association of specific class I and II allele pairings with specific phenotypes of NVP HSR, and cellular studies showing both CD4+ and CD8+ T-cell NVP-specific responses suggest that specific combinations of N VP reactive class I restrictedCD8+ and class II restrictedCD4+ T cells contribute to the immunopathogenesis of Nvp HSR.