T
Tim T. Binnewies
Researcher at Technical University of Denmark
Publications - 24
Citations - 1558
Tim T. Binnewies is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Genome & Bacterial genome size. The author has an hindex of 14, co-authored 24 publications receiving 1477 citations. Previous affiliations of Tim T. Binnewies include Hoffmann-La Roche.
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Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq.
Alexandra Sittka,Sacha Lucchini,Kai Papenfort,Cynthia M. Sharma,Katarzyna Rolle,Tim T. Binnewies,Jay C. D. Hinton,Jörg Vogel +7 more
TL;DR: This work found that the mRNAs of hilD (master regulator of the SPI-1 invasion genes) and flhDC (flagellar master regulator) were bound by Hfq, and presented a generic strategy that is ideal for the systems-level analysis of the post-transcriptional regulons of RNA-binding proteins and for sRNA discovery in a wide range of bacteria.
Journal ArticleDOI
The Complete Genome Sequence and Analysis of the Epsilonproteobacterium Arcobacter butzleri
William G. Miller,Craig T. Parker,Marc Rubenfield,George L. Mendz,Marc M. S. M. Wösten,David W. Ussery,John F. Stolz,Tim T. Binnewies,Peter Fischer Hallin,Guilin Wang,Joel A. Malek,Andrea Rogosin,Larry H. Stanker,Robert E. Mandrell +13 more
TL;DR: The presence of pathways and loci associated often with non-host-associated organisms, as well as genes associated with virulence, suggests that A. butzleri is a free-living, water-borne organism that might be classified rightfully as an emerging pathogen.
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Ten years of bacterial genome sequencing: comparative-genomics-based discoveries
Tim T. Binnewies,Yair Motro,Peter Fischer Hallin,Ole Lund,David S. Dunn,Tom La,David J. Hampson,Matthew I. Bellgard,Trudy M. Wassenaar,David W. Ussery +9 more
TL;DR: It has become clear that a genome sequence represents more than just a collection of gene sequences for an organism and that information concerning the environment and growth conditions for the organism are important for interpretation of the genomic data.
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Molecular analysis of the emergence of pandemic Vibrio parahaemolyticus
E. Fidelma Boyd,Ana Luisa V. Cohen,Ana Luisa V. Cohen,Lynn M. Naughton,Lynn M. Naughton,David W. Ussery,Tim T. Binnewies,O. Colin Stine,Michelle A. Parent +8 more
TL;DR: The data show that there is considerable genomic flux in this species and that the new highly virulent clone arose from an O3:K6 isolate that acquired at least seven novel regions, which included both a T3SS and a T6SS.
Journal ArticleDOI
The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571
Kyung-Bum Lee,Kyung-Bum Lee,Philippe De Backer,Philippe De Backer,Toshihiro Aono,Chi-Te Liu,Shino Suzuki,Tadahiro Suzuki,Takakazu Kaneko,Manabu Yamada,Satoshi Tabata,Doris M. Kupfer,Fares Z. Najar,Graham B. Wiley,Bruce A. Roe,Tim T. Binnewies,David W. Ussery,Wim D'Haeze,Jeroen Den Herder,Jeroen Den Herder,Dirk Gevers,Dirk Gevers,Dirk Gevers,Danny Vereecke,Danny Vereecke,Marcelle Holsters,Marcelle Holsters,Hiroshi Oyaizu +27 more
TL;DR: The genome analysis reveals that A. caulinodans is a diazotroph that acquired the capacity to nodulate most probably through horizontal gene transfer of a complex symbiosis island, which makes it an attractive organism to explore symbiotic biological nitrogen fixation beyond leguminous plants.