Deborah S. Nichols-Larsen

TL;DR: The Extremity Constraint Induced Therapy Evaluation (EXCITE) trial as mentioned in this paper showed that a 2-week program of constraint-induced movement therapy (CIMT) for patients more than 1 year after stroke who maintain some hand and wrist movement can improve upper extremity function that persists for at least 1 year.

TL;DR: Although results may not generalize to lower functioning stroke survivors, individual characteristics of persons with mild to moderate stroke may be important to consider in developing comprehensive, targeted interventions designed to maximize recovery and improve HRQOL.

TL;DR: Patients who have mild to moderate impairments 3-9 months poststroke have substantial improvement in functional use of the paretic upper limb and quality of life 2 years after a 2-week CIMT intervention, suggesting this intervention has persistent benefits.

TL;DR: This first multi-center effort to measure cortical reorganization induced by CIMT in subjects who are in the subacute stage of recovery produced statistically significant and clinically relevant improvements in arm motor function that persisted for at least 4 months.

TL;DR: Both patient groups achieved approximately the same level of significant arm motor function 24 months after enrollment, and both groups showed greater improvement than the delayed CIMT group in Wolf Motor Function Test Performance Time and the Motor Activity Log.