Dena Esfandyari

TL;DR: It is shown that microRNA-29 can also enhance fibrotic signalling and pathological hypertrophy of the heart through its action in cardiomyocytes and cell- or tissue-specific antimiR-29 delivery may have therapeutic value for pathological cardiac remodeling and fibrosis.

TL;DR: In this article, the role of noncoding RNA in macrophages in myocardial homeostasis and disease has been investigated and shown to be important in the regulation of macrophage migration.

TL;DR: Macrophage fate-mapping analysis with single-cell RNA sequencing is combined to establish their cellular identity during homeostasis, and in response to angiotensin-II (AngII)-induced arterial inflammation, to contribute to the understanding of macrophage heterogeneity.

TL;DR: In this article , the authors identify microRNAs that regulate the human cardiac action potential and ask whether their manipulation allows for therapeutic modulation of action potential abnormalities, such as malignant cardiac arrhythmias and sudden cardiac death.

TL;DR: In this paper , the authors identify microRNAs that regulate the human cardiac action potential and ask whether their manipulation allows for therapeutic modulation of action potential abnormalities, such as malignant cardiac arrhythmias and sudden cardiac death.