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Andreas-David Brunner
Researcher at Max Planck Society
Publications - 28
Citations - 2342
Andreas-David Brunner is an academic researcher from Max Planck Society. The author has contributed to research in topics: Proteome & Ion-mobility spectrometry. The author has an hindex of 11, co-authored 27 publications receiving 1352 citations. Previous affiliations of Andreas-David Brunner include University of Stuttgart & Technische Universität München.
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Journal ArticleDOI
Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer *
Florian Meier,Andreas-David Brunner,Scarlet Koch,Heiner Koch,Markus Lubeck,Michael Krause,Niels Goedecke,Jens Decker,Thomas Kosinski,Melvin A. Park,Nicolai Bache,Ole Hoerning,Jürgen Cox,Oliver Raether,Matthias Mann,Matthias Mann +15 more
TL;DR: The timsTOF Pro instrument is introduced, which optimally implements online PASEF and features an orthogonal ion path into the ion mobility device, limiting the amount of debris entering the instrument and making it very robust in daily operation.
Journal ArticleDOI
High-Precision Nanoscale Temperature Sensing Using Single Defects in Diamond
Philipp Neumann,Ingmar Jakobi,Florian Dolde,Christian Burk,Rolf Reuter,G. Waldherr,Jan Honert,Thomas Wolf,Andreas-David Brunner,J. H. Shim +9 more
TL;DR: In this paper, a novel nanoscale temperature sensing technique based on optically detected electron spin resonance in single atomic defects in diamonds has been proposed to measure the heat produced by chemical interactions involving a few or single molecules.
Journal ArticleDOI
Pervasive functional translation of noncanonical human open reading frames
Jin Chen,Andreas-David Brunner,J. Zachery Cogan,James K. Nuñez,Alexander P. Fields,Britt Adamson,Daniel N. Itzhak,Jason Y. Li,Matthias Mann,Matthias Mann,Manuel D. Leonetti,Jonathan S. Weissman +11 more
TL;DR: A systematic CRISPR-based screening strategy is exploited to identify hundreds of noncanonical CDSs that are essential for cellular growth and whose disruption elicits specific, robust transcriptomic and phenotypic changes in human cells.
Journal ArticleDOI
diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition
Florian Meier,Andreas-David Brunner,Max Frank,Annie Ha,Isabell Bludau,Eugenia Voytik,Stephanie Kaspar-Schoenefeld,Markus Lubeck,Oliver Raether,Nicolai Bache,Ruedi Aebersold,Ruedi Aebersold,Ben C. Collins,Ben C. Collins,Hannes L. Röst,Matthias Mann,Matthias Mann +16 more
TL;DR: This work uses the correlation of molecular weight and ion mobility in a trapped ion mobility device to devise a scan mode that samples up to 100% of the peptide precursor ion current in m/z and mobility windows and thereby increase the specificity for precursor identification.
Journal ArticleDOI
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.
Yassine Sassi,Yassine Sassi,Petros Avramopoulos,Deepak Ramanujam,Laurenz Grüter,Stanislas Werfel,Simon Giosele,Andreas-David Brunner,Dena Esfandyari,Aikaterini S. Papadopoulou,Aikaterini S. Papadopoulou,Bart De Strooper,Bart De Strooper,Norbert Hubner,Norbert Hubner,Regalla Kumarswamy,Thomas Thum,Xiaoke Yin,Manuel Mayr,Bernhard Laggerbauer,Stefan Engelhardt +20 more
TL;DR: It is shown that microRNA-29 can also enhance fibrotic signalling and pathological hypertrophy of the heart through its action in cardiomyocytes and cell- or tissue-specific antimiR-29 delivery may have therapeutic value for pathological cardiac remodeling and fibrosis.