D
Denis Spelman
Researcher at Monash University
Publications - 196
Citations - 8871
Denis Spelman is an academic researcher from Monash University. The author has contributed to research in topics: Endocarditis & Intensive care. The author has an hindex of 44, co-authored 191 publications receiving 7940 citations. Previous affiliations of Denis Spelman include University of Melbourne & Alfred Hospital.
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Journal ArticleDOI
Staphylococcus aureus Endocarditis A Consequence of Medical Progress
Vance G. Fowler,José M. Miró,Bruno Hoen,Christopher H. Cabell,Elias Abrutyn,Ethan Rubinstein,G. Ralph Corey,Denis Spelman,Suzanne F. Bradley,Bruno Baršić,Paul A. Pappas,Kevin J. Anstrom,Dannah Wray,Claudio Querido Fortes,Ignasi Anguera,Eugene Athan,Philip Jones,Jan van der Meer,Tom S.J. Elliott,Donald P. Levine,Arnold S. Bayer +20 more
TL;DR: Characteristics of patients with S aureus IE vary significantly by region, and further studies are required to determine the causes of regional variation.
Journal ArticleDOI
Heteroresistance to Colistin in Multidrug-Resistant Acinetobacter baumannii
Jian Li,Craig R Rayner,Roger L. Nation,Roxanne J. Owen,Denis Spelman,Kar Eng Tan,Lisa Liolios +6 more
TL;DR: These findings give a strong warning that colistin-resistant A. baumannii may be observed more frequently due to potential suboptimal dosage regimens recommended in the product information of some products ofcolistin methanesulfonate.
Journal ArticleDOI
Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients.
Claire L. Gorrie,Mirjana Mirceta,Ryan R. Wick,David J Edwards,Nicholas R. Thomson,Richard A. Strugnell,Nigel F. Pratt,Jill S. Garlick,Kerri M. Watson,David Pilcher,David Pilcher,Steve A. McGloughlin,Steve A. McGloughlin,Denis Spelman,Adam Jenney,Kathryn E. Holt +15 more
TL;DR: Screening for colonization on admission could limit risk of infection in the colonized patient and others, as Klebsiella pneumoniae colonization is a significant risk factor for infection in ICU.
Journal ArticleDOI
Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias.
Tahaniyat Lalani,Christopher H. Cabell,Daniel K. Benjamin,Ovidiu Lasca,Christoph Naber,Vance G. Fowler,G. Ralph Corey,Vivian H. Chu,Michael Fenely,Orathai Pachirat,Ru San Tan,Richard Watkin,Adina Ionac,Asunción Moreno,Carlos A. Mestres,José H. Casabé,Natalia Chipigina,Damon P. Eisen,Denis Spelman,François Delahaye,Gail E. Peterson,Lars Olaison,Andrew Wang +22 more
TL;DR: Early surgery for NVE is associated with an in-hospital mortality benefit compared with medical therapy alone and characteristics of patients who are most likely to benefit from early surgery are identified.
Journal ArticleDOI
Current features of infective endocarditis in elderly patients: results of the International Collaboration on Endocarditis Prospective Cohort Study
Emanuele Durante-Mangoni,Suzanne F. Bradley,Christine Selton-Suty,Marie Francoise Tripodi,Bruno Baršić,Emilio Bouza,Christopher H. Cabell,Auristela De Oliveira Ramos,Vance G. Fowler,Bruno Hoen,Pamela Konecny,Asunción Moreno,David R. Murdoch,Paul A. Pappas,Daniel J. Sexton,Denis Spelman,Pierre Tattevin,José M. Miró,Jan van der Meer,Riccardo Utili +19 more
TL;DR: Increasing age emerges as a major determinant of the clinical characteristics of infective endocarditis, and lower rates of surgical treatment and high mortality are the most prominent features of elderly patients with IE.