D
Derek Miller
Researcher at National Institutes of Health
Publications - 66
Citations - 2684
Derek Miller is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 24, co-authored 48 publications receiving 1768 citations. Previous affiliations of Derek Miller include Washington University in St. Louis & Bayer.
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Journal ArticleDOI
Spatial and Temporal Organization of the Individual Human Cerebellum
Scott Marek,Joshua S. Siegel,Evan M. Gordon,Evan M. Gordon,Ryan V. Raut,Caterina Gratton,Dillan J. Newbold,Mario Ortega,Timothy O. Laumann,Babatunde Adeyemo,Derek Miller,Annie Zheng,Katherine C. Lopez,Jeffrey J. Berg,Rebecca S. Coalson,Annie L. Nguyen,Donna L. Dierker,Andrew N. Van,Catherine R. Hoyt,Kathleen B. McDermott,Scott A. Norris,Joshua S. Shimony,Abraham Z. Snyder,Steven M. Nelson,Steven M. Nelson,M Deanna,Bradley L. Schlaggar,Marcus E. Raichle,Steven E. Petersen,Deanna J. Greene,Nico U.F. Dosenbach +30 more
TL;DR: Temporally, all cerebellar resting state signals lagged behind the cerebral cortex, supporting the hypothesis that the cerebellum engages in a domain-general function in the adaptive control of all cortical processes.
Journal ArticleDOI
Antitumor activity of sorafenib in FLT3-driven leukemic cells.
D Auclair,Derek Miller,V Yatsula,W Pickett,Christopher A. Carter,Y Chang,Xiaomei Zhang,D Wilkie,A Burd,H Shi,S Rocks,Richard W. Gedrich,L Abriola,H Vasavada,Mark Lynch,Jacques Dumas,P A Trail,Scott Wilhelm +17 more
TL;DR: The demonstration that sorafenib exhibits potent target inhibition and efficacy in FLT3-driven models suggests that this compound may have a therapeutic benefit for patients with FLT 3-driven leukemias.
ORIGINAL ARTICLE Antitumor activity of sorafenib in FLT3-driven leukemic cells
D Auclair,Derek Miller,V Yatsula,W Pickett,Christopher A. Carter,Y Chang,Xiaomei Zhang,D Wilkie,A Burd,H Shi,S Rocks,Richard W. Gedrich,L Abriola,H Vasavada,Mark Lynch,Jacques Dumas,P A Trail,Scott Wilhelm +17 more
TL;DR: Sorafenib (BAY 43-9006, Nexavar) has been shown to selectively inhibit the internal tandem duplication (ITD) insertions in the juxtamembrane domain of the FLT3 tyrosine kinase as mentioned in this paper.
Journal ArticleDOI
An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment.
Yi Xu,Roberto Romero,Derek Miller,Leena Kadam,Tara N. Mial,Tara N. Mial,Olesya Plazyo,Valeria Garcia-Flores,Valeria Garcia-Flores,Sonia S. Hassan,Sonia S. Hassan,Zhonghui Xu,Zhonghui Xu,Adi L. Tarca,Adi L. Tarca,Sascha Drewlo,Nardhy Gomez-Lopez,Nardhy Gomez-Lopez +17 more
TL;DR: It is demonstrated that decidual M1-like macrophages are associated with spontaneous preterm labor and that PPARγ activation via RSG can attenuate the macrophage-mediated proinflammatory response, preventing preterm birth and improving neonatal outcomes.
Journal ArticleDOI
Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth.
Nardhy Gomez-Lopez,Nardhy Gomez-Lopez,Roberto Romero,Olesya Plazyo,Olesya Plazyo,Bogdan Panaitescu,Amy Eunice Furcron,Amy Eunice Furcron,Derek Miller,Derek Miller,Tamara Roumayah,Emily Flom,Sonia S. Hassan,Sonia S. Hassan +13 more
TL;DR: The aim of this study was to determine whether intra‐amniotic administration of an alarmin, HMGB1, could induce preterm labor/birth.