D
Dhara Malavia
Researcher at University of Exeter
Publications - 6
Citations - 116
Dhara Malavia is an academic researcher from University of Exeter. The author has contributed to research in topics: Antifungal drug & Gene. The author has an hindex of 4, co-authored 4 publications receiving 73 citations. Previous affiliations of Dhara Malavia include University of Aberdeen.
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Book ChapterDOI
Nutritional Immunity and Fungal Pathogenesis: The Struggle for Micronutrients at the Host-Pathogen Interface.
TL;DR: In this article, the authors explore the nutritional immune mechanisms that defend the human body against fungal infections and the strategies that these important pathogens exploit to counteract nutritional immunity and thrive in the infected host.
Journal ArticleDOI
Zinc Limitation Induces a Hyper-Adherent Goliath Phenotype in Candida albicans
Dhara Malavia,Laura E. Lehtovirta-Morley,Laura E. Lehtovirta-Morley,Omran Alamir,Elisabeth Weiß,Neil A. R. Gow,Bernhard Hube,Bernhard Hube,Duncan Wilson +8 more
TL;DR: Interestingly, the zincophore-encoding gene PRA1 was expressed by Goliath cells in zinc limited media and lack of Pra1 inhibited both cellular enlargement and adhesion, suggesting a possible role in pathogenicity.
Journal ArticleDOI
Biosensors and Diagnostics for Fungal Detection.
Khalil K. Hussain,Dhara Malavia,Elizabeth M. Johnson,Elizabeth M. Johnson,Jennifer A. Littlechild,C. Peter Winlove,Frank Vollmer,Neil A. R. Gow +7 more
TL;DR: This overview provides a critical review of current fungal diagnostics and the development of new biophysical technologies that are being applied for selective new sensitive fungal biosensors to augment traditional diagnostic methodologies.
Journal ArticleDOI
Advances in Molecular Tools and In Vivo Models for the Study of Human Fungal Pathogenesis.
TL;DR: Advances that have been made in the use of molecular tools using CRISPR technologies, RNA interference and transposon targeted mutagenesis are highlighted, focusing on zebrafish, the silkworm, Galleria mellonella and the murine model.
Journal ArticleDOI
SWI/SNF and the histone chaperone Rtt106 drive expression of the Pleiotropic Drug Resistance network genes
TL;DR: In this paper , the histone chaperone Rtt106 and the chromatin remodeller SWI/SNF control expression of the Pleiotropic Drug Resistance (PDR) network genes and confer drug resistance.