D
Dhirendra Kumar
Researcher at National Institutes of Health
Publications - 42
Citations - 1232
Dhirendra Kumar is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Genome & Proteogenomics. The author has an hindex of 17, co-authored 34 publications receiving 973 citations. Previous affiliations of Dhirendra Kumar include Council of Scientific and Industrial Research & QIMR Berghofer Medical Research Institute.
Papers
More filters
Journal ArticleDOI
Proteogenomic Analysis of Mycobacterium tuberculosis By High Resolution Mass Spectrometry
Dhanashree S. Kelkar,Dhirendra Kumar,Praveen Kumar,Lavanya Balakrishnan,Babylakshmi Muthusamy,Amit Kumar Yadav,Priyanka Shrivastava,Arivusudar Marimuthu,S. Anand,Hema Sundaram,Reena Kingsbury,H. C. Harsha,Bipin G. Nair,T. S. Keshava Prasad,T. S. Keshava Prasad,Devendra Singh Chauhan,Kiran Katoch,Vishwa Mohan Katoch,P. Kumar,Raghothama Chaerkady,Srinivasan Ramachandran,Debasis Dash,Akhilesh Pandey +22 more
TL;DR: An in-depth proteogenomic analysis of the M. tuberculosis H37Rv strain using Fourier transform mass spectrometry with high resolution at both MS and tandem MS levels identified 3176 proteins from Mycobacterium tuberculosis representing ∼80% of its total predicted gene count.
Journal ArticleDOI
Integrating transcriptome and proteome profiling: Strategies and applications
Dhirendra Kumar,G. Bansal,Ankita Narang,Trayambak Basak,Trayambak Basak,Tahseen Abbas,Tahseen Abbas,Debasis Dash,Debasis Dash +8 more
TL;DR: Improvements in “big‐data” analysis techniques enable novel conclusions to be drawn from integrative transcriptomic‐proteomic analysis of high‐throughput omics methods.
Journal ArticleDOI
Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency.
Pengyi Yang,Pengyi Yang,Sean J. Humphrey,Sean J. Humphrey,Senthilkumar Cinghu,Rajneesh Pathania,Andrew J. Oldfield,Dhirendra Kumar,Dinuka Perera,Jean Yee Hwa Yang,David E. James,Matthias Mann,Raja Jothi +12 more
TL;DR: The dynamics of pluripotent state transitions underlying pre- to post-implantation epiblast differentiation and kinase-substrate networks reveal signaling cascades, dynamics, and crosstalk in embryonic stem cells transitioning from naive to primed pluripotency.
Journal ArticleDOI
Transcriptome and venom proteome of the box jellyfish Chironex fleckeri.
Diane L. Brinkman,Xinying Jia,Jeremy Potriquet,Dhirendra Kumar,Dhirendra Kumar,Debasis Dash,David Kvaskoff,Jason Mulvenna,Jason Mulvenna +8 more
TL;DR: This study provides the first overview of a box Jellyfish transcriptome which, coupled with venom proteomics data, enhances the current understanding of box jellyfish venom composition and the molecular structure and function of cnidarian toxins.
Journal ArticleDOI
A systematic analysis of eluted fraction of plasma post immunoaffinity depletion: implications in biomarker discovery.
Amit Kumar Yadav,Gourav Bhardwaj,Trayambak Basak,Dhirendra Kumar,Shadab Ahmad,Ruby Priyadarshini,Ashish Kumar Singh,Debasis Dash,Shantanu Sengupta +8 more
TL;DR: It is believed that for biomarker discovery and proper quantitation of proteins, it might be better to study both bound and depleted fractions from any MARS depleted plasma sample.