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Diane van der Woude
Researcher at Leiden University Medical Center
Publications - 65
Citations - 3925
Diane van der Woude is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Anti–citrullinated protein antibody & Autoantibody. The author has an hindex of 28, co-authored 64 publications receiving 3319 citations. Previous affiliations of Diane van der Woude include Leiden University & Brigham and Women's Hospital.
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Journal ArticleDOI
Long-Term Impact of Delay in Assessment of Patients With Early Arthritis
Michael P M van der Linden,Saskia le Cessie,Karim Raza,Diane van der Woude,Rachel Knevel,Tom W J Huizinga,Annette H M van der Helm-van Mil +6 more
TL;DR: Assessment in <12 weeks is associated with less joint destruction and a higher chance of achieving DMARD-free remission as compared with a longer delay in assessment, implying that attempts to diminish the delay in seeing a rheumatologist will improve disease outcome in patients with RA.
Journal ArticleDOI
Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis
Diane van der Woude,Solbritt Rantapää-Dahlqvist,Andreea Ioan-Facsinay,Carla Onnekink,Carla M. Schwarte,Kirsten N Verpoort,Jan W. Drijfhout,Tom Huizinga,René E. M. Toes,Ger J. M. Pruijn +9 more
TL;DR: Epitope spreading with an increase in the recognition of citrullinated antigens occurs before the onset of RA, and immunological differences in ACPA fine specificity between UA–UA patients and UA–RA patients are associated with the future disease course.
Journal ArticleDOI
Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.
Diane van der Woude,Jeanine J. Houwing-Duistermaat,René E. M. Toes,Tom W J Huizinga,Wendy Thomson,Jane Worthington,Annette H M van der Helm-van Mil,René R. P. de Vries +7 more
TL;DR: The data indicate that genetic predisposition plays an important role in the pathogenesis of ACPA-negative RA, for which most individual genetic risk factors remain to be identified.
Journal ArticleDOI
Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis.
TL;DR: The latest insights into epidemiology, risk factors, predisease states, and outcomes are discussed, with more emphasis on sustained drug-free remission and patient-reported outcomes.
Journal ArticleDOI
Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives
Carol A. Hitchon,Fatiha Chandad,Elizabeth D. Ferucci,Annemiek Willemze,Andreea Ioan-Facsinay,Diane van der Woude,Janet Markland,David Robinson,Brenda Elias,Marianna M. Newkirk,René E. M. Toes,Tom W J Huizinga,Hani El-Gabalawy +12 more
TL;DR: In a genetically predisposed population of NAN patients with RA and their relatives, anti-P.