D
Dianne Cox
Researcher at Albert Einstein College of Medicine
Publications - 72
Citations - 5679
Dianne Cox is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Macrophage & Phagocytosis. The author has an hindex of 39, co-authored 69 publications receiving 5249 citations. Previous affiliations of Dianne Cox include Columbia University.
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Journal ArticleDOI
Macrophages Promote the Invasion of Breast Carcinoma Cells via a Colony-Stimulating Factor-1/Epidermal Growth Factor Paracrine Loop
Sumanta Goswami,Erik Sahai,Erik Sahai,Jeffrey B. Wyckoff,Michael Cammer,Dianne Cox,Fiona J. Pixley,E. Richard Stanley,Jeffrey E. Segall,John S. Condeelis +9 more
TL;DR: It is shown that macrophages and tumor cells are necessary and sufficient for comigration and invasion into collagen I and that this process involves a paracrine loop.
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Requirements for Both Rac1 and Cdc42 in Membrane Ruffling and Phagocytosis in Leukocytes
TL;DR: In this article, the authors demonstrate differential requirements for Rho family GTPases in leukocyte motility, and indicate that both Rac1 and Cdc42 are required for Fc γ receptor mediated phagocytosis and for membrane ruffling mediated by structurally distinct receptors in macrophages.
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A Requirement for Phosphatidylinositol 3-Kinase in Pseudopod Extension
TL;DR: Results indicate that one or more isoforms of PI 3 kinase are required for maximal pseudopod extension but not phagocytosis per se, and suggest that PI 3-kinase is required for coordinating exocytic membrane insertion and pseudobod extension.
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A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis
TL;DR: It is concluded that macrophages have adapted a rapidly mobilizable, endocytic compartment to enhance phagocytosis.
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Myosin X is a downstream effector of PI(3)K during phagocytosis
Dianne Cox,Jonathan S. Berg,Michael Cammer,John O. Chinegwundoh,Benjamin M. Dale,Richard E. Cheney,Steven Greenberg +6 more
TL;DR: It is proposed that Myo10 provides a molecular link between PI(3)K and pseudopod extension during phagocytosis and is recruited tophagocytic cups in a wortmannin-sensitive manner.