Peter Chang

TL;DR: In this article, the authors demonstrate differential requirements for Rho family GTPases in leukocyte motility, and indicate that both Rac1 and Cdc42 are required for Fc γ receptor mediated phagocytosis and for membrane ruffling mediated by structurally distinct receptors in macrophages.

TL;DR: For The Cancer Imaging Archives dataset, machine-learning approaches allow classification of individual genetic mutations of both low- and high-grade gliomas and relevant MR imaging features acquired from an added dimensionality-reduction technique demonstrate that neural networks are capable of learning key imaging components without prior feature selection or human directed training.

TL;DR: The coordinated tyrosine phosphorylation of the gamma subunit of macrophage Fc receptors, the tyrosin kinase syk, and the cytoskeletal-associated protein, paxillin, may be important steps in integrating signals between Fc receptor and the underlying cytoskeleton.

TL;DR: It is suggested that tyrosine phosphorylation is a critical signaling event that underlies Fc receptor-mediated phagocytosis in mouse macrophages, and is necessary for the engulfment per se.

TL;DR: Demonstrated high performance on prospective NCCTs ordered from the emergency department suggests the clinical viability of the proposed deep learning tool in the detection and quantification of hemorrhage on NCCT.