D
Dimple Bansal
Researcher at Brigham and Women's Hospital
Publications - 14
Citations - 2203
Dimple Bansal is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myeloid leukemia & ITGA7. The author has an hindex of 11, co-authored 13 publications receiving 2058 citations. Previous affiliations of Dimple Bansal include University of Iowa & Roy J. and Lucille A. Carver College of Medicine.
Papers
More filters
Journal ArticleDOI
Defective membrane repair in dysferlin-deficient muscular dystrophy
Dimple Bansal,Katsuya Miyake,Steven S. Vogel,Séverine Groh,Chien-Chang Chen,Roger A. Williamson,Paul L. McNeil,Kevin P. Campbell +7 more
TL;DR: It is shown that disruption of the muscle membrane repair machinery is responsible for dysferlin-deficient muscle degeneration, and the importance of this basic cellular mechanism of membrane resealing in human disease is highlighted.
Journal ArticleDOI
Disruption of the Sarcoglycan–Sarcospan Complex in Vascular Smooth Muscle: A Novel Mechanism for Cardiomyopathy and Muscular Dystrophy
Ramón Mauricio Coral-Vázquez,Ronald D. Cohn,Steven A. Moore,Joseph A. Hill,Robert M. Weiss,Robert M. Weiss,Robin L. Davisson,Volker Straub,R. Barresi,Dimple Bansal,Ron F. Hrstka,Roger A. Williamson,Kevin P. Campbell +12 more
TL;DR: The data indicate that disruption of the SG-SSPN complex in vascular smooth muscle perturbs vascular function, which initiates cardiomyopathy and exacerbates muscular dystrophy.
Journal ArticleDOI
Dysferlin and the plasma membrane repair in muscular dystrophy
Dimple Bansal,Kevin P. Campbell +1 more
TL;DR: The current knowledge of dysferlin function in the repair of the plasma membrane of the skeletal muscle cells is discussed and it is demonstrated that defective membrane repair is a novel mechanism of muscle degeneration.
Journal ArticleDOI
Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injury
Renzhi Han,Dimple Bansal,Dimple Bansal,Katsuya Miyake,Viviane P. Muniz,Robert M. Weiss,Paul L. McNeil,Kevin P. Campbell +7 more
TL;DR: This study establishes what it believes is a novel mechanism underlying the cardiomyopathy that results from a defective membrane repair in the absence of dysferlin, and suggests that Dysferlin-mediated membrane repair is important for maintaining membrane integrity of cardiomers, particularly under conditions of mechanical stress.
Journal ArticleDOI
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
Claudia Scholl,Dimple Bansal,Konstanze Döhner,Karina Eiwen,Brian J. P. Huntly,Benjamin H. Lee,Frank G. Rücker,Richard F. Schlenk,Lars Bullinger,Hartmut Döhner,D. Gary Gilliland,Stefan Fröhling +11 more
TL;DR: It is demonstrated that aberrant expression of the developmental regulatory gene CDX2 in the adult hematopoietic compartment is a frequent event in the pathogenesis of AML and support the hypothesis that CDx2 is responsible, in part, for the altered HOX gene expression that is observed in most cases ofAML.