D
Dirk Arnold
Researcher at Leipzig University
Publications - 249
Citations - 16651
Dirk Arnold is an academic researcher from Leipzig University. The author has contributed to research in topics: Colorectal cancer & Bevacizumab. The author has an hindex of 40, co-authored 218 publications receiving 11640 citations.
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ESMO consensus guidelines for the management of patients with metastatic colorectal cancer
E. Van Cutsem,Andrés Cervantes,René Adam,Alberto Sobrero,J.H.J.M. van Krieken,Dan Aderka,E. Aranda Aguilar,Alberto Bardelli,Al B. Benson,György Bodoky,Fortunato Ciardiello,André D'Hoore,Eduardo Díaz-Rubio,J.-Y. Douillard,Michel Ducreux,Alfredo Falcone,Axel Grothey,Thomas Gruenberger,Karin Haustermans,Volker Heinemann,Paulo M. Hoff,C.-H. Köhne,R. Labianca,Pierre Laurent-Puig,Brigette B.Y. Ma,Tim Maughan,Kei Muro,Nicola Normanno,Pia Österlund,Pia Österlund,Wim J.G. Oyen,Demetris Papamichael,George Pentheroudakis,Per Pfeiffer,Timothy J. Price,C.J.A. Punt,Jens Ricke,Arnaud Roth,R. Salazar,Werner Scheithauer,H.-J. Schmoll,Josep Tabernero,Julien Taieb,Sabine Tejpar,Harpreet Wasan,Takayuki Yoshino,Aziz Zaanan,Dirk Arnold +47 more
TL;DR: These ESMO consensus guidelines have been developed based on the current available evidence to provide a series of evidence-based recommendations to assist in the treatment and management of patients with mCRC in this rapidly evolving treatment setting.
Journal ArticleDOI
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer
Talia Golan,Pascal Hammel,Michele Reni,Eric Van Cutsem,Teresa Macarulla,Michael J. Hall,Joon Oh Park,Daniel Hochhauser,Dirk Arnold,Do Youn Oh,Anke Reinacher-Schick,Giampaolo Tortora,Giampaolo Tortora,Hana Algül,Eileen M. O'Reilly,David McGuinness,Karen Y. Cui,Katia Schlienger,Gershon Y. Locker,Hedy L. Kindler +19 more
TL;DR: Among patients with a germline BRCA mutation and metastatic pancreatic cancer, progression-free survival was longer with maintenance olaparib than with placebo, and there was no significant between-group difference in health-related quality of life.
Journal ArticleDOI
Early colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
R. Labianca,Bernard Nordlinger,Giordano D. Beretta,Stefania Mosconi,Mario Mandalà,Andrés Cervantes,Dirk Arnold +6 more
TL;DR: This work presents a meta-analyses of the prophylactic and descriptive literature reviews that show clear trends in prognosis for atypical central giant cell granuloma in women and suggest that once these patterns are identified, the prognosis is poor for other types of cancers.
Journal ArticleDOI
Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial
Jaafar Bennouna,Javier Sastre,Dirk Arnold,Pia Österlund,Richard Greil,Eric Van Cutsem,Roger von Moos,Jose María Vieitez,Olivier Bouché,Christophe Borg,Claus-Christoph Steffens,V. Alonso-Orduna,Christoph Schlichting,Irmarie Reyes-Rivera,Belguendouz Bendahmane,Thierry André,Stefan Kubicka +16 more
TL;DR: Maintenance of VEGF inhibition with bevacizumab plus standard second-line chemotherapy beyond disease progression has clinical benefits in patients with metastatic colorectal cancer.
Journal ArticleDOI
Cancer of the pancreas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Michel Ducreux,Michel Ducreux,A. Sa. Cuhna,Caroline Caramella,Antoine Hollebecque,Pascal Burtin,Diane Goéré,Thomas Seufferlein,Karin Haustermans,J.-L. Van Laethem,Thierry Conroy,Dirk Arnold +11 more
TL;DR: The ESMO Guidelines Committee recommends that patients with a history of atypical central giant cell granuloma be referred to a specialist oncologist for initial diagnosis and follow-up care.