D
Dirk J. Ruiter
Researcher at Radboud University Nijmegen Medical Centre
Publications - 302
Citations - 19259
Dirk J. Ruiter is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Melanoma & Metastasis. The author has an hindex of 77, co-authored 301 publications receiving 18589 citations. Previous affiliations of Dirk J. Ruiter include Praxis & Radboud University Nijmegen.
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Journal ArticleDOI
How schema and novelty augment memory formation.
Marlieke T. R. van Kesteren,Marlieke T. R. van Kesteren,Dirk J. Ruiter,Guillén Fernández,Guillén Fernández,Richard N. Henson +5 more
TL;DR: Lesion and neuroimaging findings in animals and humans that relate to the apparent paradoxical relationship between schema and novelty and a framework relating key brain regions in medial temporal lobe and medial prefrontal cortex during encoding, consolidation and retrieval of information as a function of its congruency with existing information represented in neocortex are reviewed.
Journal ArticleDOI
Matrix Metalloproteinases in Human Melanoma
TL;DR: It is concluded that the balance between levels of activated matrix metalloproteinases and expression levels of their tissue inhibitors, and the coexpression of activates and adhesion molecules are important factors in determining melanoma cell invasion, tumor growth, and metastasis formation.
Journal Article
Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients
I. Jolanda M. de Vries,W. Joost Lesterhuis,Nicole M. Scharenborg,Linda P. H. Engelen,Dirk J. Ruiter,Marie-Jeanne P. Gerritsen,Sandra Croockewit,Cedrik M. Britten,Ruurd Torensma,Gosse J. Adema,Carl G. Figdor,Cornelis J. A. Punt +11 more
TL;DR: It is concluded that mature DC are superior to immature DC in the induction of immunological responses in melanoma patients, which may translate into improved clinical results.
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Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial.
Alexander M.M. Eggermont,Stefan Suciu,Rona M. MacKie,Wlodzimierz Ruka,Alessandro Testori,Wim H. J. Kruit,Cornelis J. A. Punt,Michelle Delauney,François Sales,Gerard Groenewegen,Dirk J. Ruiter,Izabella Jagiello,Konstantin Stoitchkov,Ulrich Keilholz,Danielle Lienard +14 more
TL;DR: Interferon alfa as used in the regimens studied does not improve outcome for patients with stage IIb/III melanomas, and cannot be recommended.
Journal Article
Coexpression of intermediate filament polypeptides in human fetal and adult tissues.
TL;DR: It is indicated that coexpression of different types of intermediate filaments is a more general phenomenon in fetal tissues than previously realized and it also occurs in some reactive proliferative lesions in the adult.