G
George P. Daston
Researcher at Procter & Gamble
Publications - 32
Citations - 4552
George P. Daston is an academic researcher from Procter & Gamble. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 20, co-authored 24 publications receiving 4106 citations. Previous affiliations of George P. Daston include Salk Institute for Biological Studies & University of Konstanz.
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Journal ArticleDOI
Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern
Laufersweiler Michael Christopher,Bernard Gadagbui,Irene M. Baskerville-Abraham,Andrew Maier,Alison Willis,Anthony R. Scialli,Gregory J. Carr,Susan P. Felter,Karen Blackburn,George P. Daston +9 more
TL;DR: This work expands the database of chemicals with reproductive and developmental data, presents these data in a comprehensive and transparent format and groups the chemicals according to the TTC "Cramer Class" rules.
Journal ArticleDOI
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
Sarah Adler,David A. Basketter,Stuart Creton,Olavi Pelkonen,Jan van Benthem,Valérie Zuang,Klaus Ejner Andersen,Alexandre Angers-Loustau,Aynur O. Aptula,Anna Bal-Price,Emilio Benfenati,Ulrike Bernauer,J.G.M. Bessems,Frédéric Y. Bois,Alan R. Boobis,Esther Brandon,Susanne Bremer,Thomas H. Broschard,Silvia Casati,Sandra Coecke,Raffaella Corvi,Mark T. D. Cronin,George P. Daston,Wolfgang Dekant,Susan P. Felter,Elise Grignard,Ursula Gundert-Remy,Tuula Heinonen,Ian Kimber,Jos C. S. Kleinjans,Hannu Komulainen,Reinhard Kreiling,Joachim Kreysa,Sofia B. Leite,George Loizou,Gavin Maxwell,Paolo Mazzatorta,Sharon Munn,Stefan Pfuhler,Pascal Phrakonkham,Aldert H. Piersma,Albrecht Poth,Pilar Prieto,Guillermo Repetto,Vera Rogiers,Greet Schoeters,Michael Schwarz,Rositsa Serafimova,Hanna Tähti,Emanuela Testai,Joost H.M. van Delft,Henk Van Loveren,Mathieu Vinken,Andrew Worth,Jose-Manuel Zaldivar +54 more
TL;DR: In this paper, Adler et al. present a survey of the authors' work in the field of bioinformatics, including the following authors:Sarah AdlerDavid BasketterStuart CretonOlavi PelkonenJan van BenthemValerie Zuang • Klaus Ejner AndersenAlexandre Angers-LoustauAynur AptulaAnna Bal-PriceEmilio Benfenati • Ulrike BernauerJos BessemsFrederic Y. BoisAlan BoobisEsther BrandonSusanne Bremer • Thomas
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Identification and Characterization of Toxicity of Contaminants in Pet Food Leading to an Outbreak of Renal Toxicity in Cats and Dogs
Roy L. M. Dobson,Safa Motlagh,Mike Quijano,R. Thomas Cambron,Timothy R. Baker,Aletha M. Pullen,Brian T. Regg,Adrienne S. Bigalow-Kern,Thomas Vennard,Andrew S. Fix,Renate Reimschuessel,Gary J. Overmann,Yuching Shan,George P. Daston +13 more
TL;DR: The causal link between the contaminated gluten and the adverse effects of melamine and cyanuric acid is established and a mechanistic explanation for how two apparently innocuous compounds could have adverse effects in combination is provided.
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Toxicogenomics in regulatory ecotoxicology.
Gerald T. Ankley,George P. Daston,Sigmund J. Degitz,Nancy D. Denslow,Robert A. Hoke,Sean W. Kennedy,Ann L. Miracle,Edward J. Perkins,Jason Snape,Donald E. Tillitt,Charles R. Tyler,Donald J. Versteeg +11 more
TL;DR: Roles of toxicogenomics in the field of regulatory ecotoxicology are considered, current limitations in the science and practice of genomics are explored, and possible avenues to approach and resolve some of the major challenges are proposed.
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Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse
TL;DR: Results indicate that Pax-3 regulates the migration of limb muscle precursors into the limb and is not required for cells in the lateral somite to differentiate into muscle.