D
Doris Hissako Sumida
Researcher at Sao Paulo State University
Publications - 90
Citations - 2218
Doris Hissako Sumida is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Insulin resistance & Insulin. The author has an hindex of 21, co-authored 90 publications receiving 1772 citations. Previous affiliations of Doris Hissako Sumida include University of São Paulo.
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Journal ArticleDOI
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Bhagirath Chaurasia,Trevor S. Tippetts,Rafael Mayoral Monibas,Jinqi Liu,Ying Li,Liping Wang,Joseph L. Wilkerson,C. Rufus Sweeney,Renato Felipe Pereira,Doris Hissako Sumida,J. Alan Maschek,James E. Cox,Vincent A. Kaddai,Graeme I. Lancaster,Monowarul Mobin Siddique,Annelise M Poss,Mackenzie J. Pearson,Santhosh Satapati,Heather Zhou,David G. McLaren,Stephen F. Previs,Ying Chen,Ying Qian,Aleksandr Petrov,Margaret Wu,Xiaolan Shen,Jun Yao,Christian N. Nunes,Andrew D. Howard,Liangsu Wang,Mark D. Erion,Jared Rutter,Jared Rutter,William L. Holland,David E. Kelley,Scott A. Summers +35 more
TL;DR: Mechanistic studies revealed ceramide actions that promoted lipid uptake and storage and impaired glucose utilization, none of which could be recapitulated by (dihydro)ceramides that lacked the critical double bond, suggest that inhibition of DES1 may provide a means of treating hepatic steatosis and metabolic disorders.
Journal ArticleDOI
Saliva: reflection of the body.
Daniela Pereira Lima,Diego Garcia Diniz,Suzely Adas Saliba Moimaz,Doris Hissako Sumida,Ana Cláudia Okamoto +4 more
TL;DR: The value of these methods for the diagnosis of oral and systemic diseases has been the subject of study by several researchers with the aim of increasing its use alongside complementary exams.
Journal ArticleDOI
Pinealectomy causes glucose intolerance and decreases adipose cell responsiveness to insulin in rats
Fábio Bessa Lima,Ubiratan Fabres Machado,I Bartol,Patricia Monteiro Seraphim,Doris Hissako Sumida,Solange Marta Franzói de Moraes,Naomi Shinomiya Hell,Maristela Mitiko Okamoto,Mario J.A. Saad,Carla Roberta de Oliveira Carvalho,José Cipolla-Neto +10 more
TL;DR: In this article, male Wistar rats, pinealectomized or sham-operated 6 wk before the experiment, were submitted to both intravenous glucose tolerance tests (IVGTT) and insulin binding as well as glucose transport assays in isolated adipocytes.
Proceedings Article
Pinealectomy causes glucose intolerance and decreases adipose cell responsiveness to insulin in rats
Fábio Bessa Lima,Ubiratan Fabres Machado,I Bartol,Patricia Monteiro Seraphim,Doris Hissako Sumida,Solange Marta Franzói de Moraes,Naomi Shinomiya Hell,Maristela Mitiko Okamoto,Mario J.A. Saad,Carla Roberta de Oliveira Carvalho,José Cipolla-Neto +10 more
TL;DR: P pinealectomy is responsible for both impaired insulin secretion and action, emphasizing the influence of the pineal gland on glucose metabolism.
Journal ArticleDOI
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
Bhagirath Chaurasia,Trevor S. Tippetts,Mayoral Monibas R,Liu J,Youyou Li,Wang L,Joseph L. Wilkerson,Sweeney Cr,Renato Felipe Pereira,Doris Hissako Sumida,John Alan Maschek,James E. Cox,Kaddai,Graeme I. Lancaster,Monowarul Mobin Siddique,Annelise M Poss,Mackenzie J. Pearson,Santhosh Satapati,Zhou H,David G. McLaren,Stephen F. Previs,Chen Y,Qian Y,Aleksandr Petrov,Wu M,Shen X,Yao J,Christian N. Nunes,Andrew D. Howard,Erion,Jared Rutter,William L. Holland,David E. Kelley,Scott A. Summers +33 more