D
Doulaye Dembélé
Researcher at University of Strasbourg
Publications - 73
Citations - 4233
Doulaye Dembélé is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Gene expression profiling & Cellular differentiation. The author has an hindex of 28, co-authored 71 publications receiving 3772 citations. Previous affiliations of Doulaye Dembélé include French Institute of Health and Medical Research & Centre national de la recherche scientifique.
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Journal ArticleDOI
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling
Scott H. Robbins,Thierry Walzer,Thierry Walzer,Doulaye Dembélé,Christelle Thibault,Axel Defays,Axel Defays,Gilles Bessou,Gilles Bessou,Huichun Xu,Eric Vivier,MacLean Sellars,Philippe Pierre,Philippe Pierre,Franck R Sharp,Susan Chan,Philippe Kastner,Marc Dalod,Marc Dalod +18 more
TL;DR: This study seeks conserved genetic signatures for LN-DCs and in vitro derived granulocyte-macrophage colony stimulating factor (GM-CSF) DCs through the analysis of a compendium of genome-wide expression profiles of mouse or human leukocytes and identifies a large gene expression program shared between mouse and human pDCs, and smaller conserved profiles shared betweenmouse and human Ln-cDC subsets.
Journal ArticleDOI
Fuzzy C-means method for clustering microarray data
Doulaye Dembélé,Philippe Kastner +1 more
TL;DR: By setting threshold levels for the membership values of the FCM method, genes which are tigthly associated to a given cluster can be selected and this selection increases the overall biological significance of the genes within the cluster.
Journal ArticleDOI
SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas
Thomas Hussenet,Soraya Dali,Julien Exinger,Ben Monga,Bernard Jost,Bernard Jost,Bernard Jost,Doulaye Dembélé,Doulaye Dembélé,Doulaye Dembélé,Nadine Martinet,Christelle Thibault,Christelle Thibault,Christelle Thibault,Joerg Huelsken,Elisabeth Brambilla,Stanislas du Manoir +16 more
TL;DR: It is indicated that the SOX2 transcription factor, a major regulator of stem cell function, is also an oncogene and a driver gene for the recurrent 3q26.33 amplifications in lung SCC.
Journal ArticleDOI
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy
Charlotte Fugier,Arnaud F. Klein,C. Hammer,Stéphane Vassilopoulos,Ylva Ivarsson,Anne Toussaint,Valérie Tosch,Alban Vignaud,Arnaud Ferry,Nadia Messaddeq,Yosuke Kokunai,Rie Tsuburaya,Pierre de la Grange,Doulaye Dembélé,Virginie Francois,Guillaume Précigout,Charlotte Boulade-Ladame,Marie-Christine Hummel,Adolfo López de Munain,Nicolas Sergeant,Annie Laquerrière,Christelle Thibault,François Deryckere,Didier Auboeuf,Luis Garcia,Pascale Zimmermann,Bjarne Udd,Benedikt Schoser,Masanori P. Takahashi,Ichizo Nishino,Guillaume Bassez,Jocelyn Laporte,Denis Furling,Nicolas Charlet-Berguerand +33 more
TL;DR: It is found that MBNL1 binds the BIN1 pre-mRNA and regulates its alternative splicing, which helps to promote T tubule alterations and muscle weakness, a predominant feature of myotonic dystrophy.
Journal ArticleDOI
Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis.
Anne Cromer,Annaïck Carles,Régine Millon,Gitali Ganguli,Frédéric Chalmel,F Lemaire,Julia Young,Doulaye Dembélé,Christelle Thibault,Danièle Muller,Olivier Poch,Joseph Abecassis,Bohdan Wasylyk +12 more
TL;DR: This study reports the first large-scale gene expression analysis of a unique HNSCC location, the hypopharynx, and identifies 164 differentially expressed genes potentially involved in the acquisition of metastatic potential.