D
Duncan Lupiya
Researcher at Dignitas International
Publications - 4
Citations - 270
Duncan Lupiya is an academic researcher from Dignitas International. The author has contributed to research in topics: Flucytosine & Fluconazole. The author has an hindex of 3, co-authored 4 publications receiving 180 citations.
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Journal ArticleDOI
Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa
Síle F. Molloy,Cecilia Kanyama,Robert S. Heyderman,Angela Loyse,Charles Kouanfack,Duncan Chanda,Sayoki Mfinanga,Elvis Temfack,Shabir Lakhi,Sokoine Lesikari,Adrienne K. Chan,Neil Stone,Newton Kalata,Natasha Karunaharan,Katherine M Gaskell,Mary Peirse,Jayne Ellis,Chimwemwe Chawinga,Sandrine Lontsi,Jean-Gilbert Ndong,Philip Bright,Duncan Lupiya,Tao Chen,John S. Bradley,Jack Adams,Charles van der Horst,Joep J. van Oosterhout,Victor Sini,Yacouba Mapoure,Peter Mwaba,Tihana Bicanic,David G. Lalloo,Duolao Wang,Mina C. Hosseinipour,Olivier Lortholary,Shabbar Jaffar,Tom Harrison +36 more
TL;DR: Two treatment strategies that could be more sustainable in Africa than the standard of 2 weeks of amphotericin B plus flucytosine and more effective than the widely used fluconazole monotherapy were tested.
Journal ArticleDOI
One-year Mortality Outcomes From the Advancing Cryptococcal Meningitis Treatment for Africa Trial of Cryptococcal Meningitis Treatment in Malawi.
Cecilia Kanyama,Síle F. Molloy,Adrienne K. Chan,Adrienne K. Chan,Duncan Lupiya,Chimwemwe Chawinga,Jack Adams,Philip Bright,Philip Bright,David G. Lalloo,Robert S. Heyderman,Robert S. Heyderman,Robert S. Heyderman,Olivier Lortholary,Olivier Lortholary,Shabbar Jaffar,Angela Loyse,Joep J. van Oosterhout,Joep J. van Oosterhout,Mina C. Hosseinipour,Thomas S. Harrison +20 more
TL;DR: In Malawi, 236 participants from the Advancing Cryptococcal Meningitis Treatment for Africa trial were followed for 12 months and one-week amphotericin B plus flucytosine was associated with the lowest 1 year mortality.
A randomized controlled trial for the treatment of HIV-associated cryptococcal meningitis in Africa: oral fluconazole plus flucytosine or one week amphotericin-based therapy versus two weeks amphotericin-based therapy. The ACTA Trial
Síle F Molloy,Cecilia Kanyama,Robert S. Heyderman,Angela Loyse,Charles Kouanfack,Duncan Chanda,Sayoki Mfinanga,Elvis Temfack,Shabir Lakhi,Sokoine Lesikari,Adrienne K. Chan,Neil Stone,Newton Kalata,Natasha Karunaharan,Katherine M Gaskell,Mary Peirse,Jayne Ellis,Chimwemwe Chawinga,S Lontsi,J-G Ndong,Philip David Bright,Duncan Lupiya,Tao Chen,John S. Bradley,Jack Adams,C van der Horst,JJ van Oosterhout,Sini,Yacouba Mapoure,Peter Mwaba,Tihana Bicanic,David G. Lalloo,Duolao Wang,Mina Hosseinipour,Olivier Lortholary,Shabbar Jaffar,Tessa Harrison,Actats Team +37 more
Journal ArticleDOI
The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options.
Philip David Bright,Duncan Lupiya,Joep J. van Oosterhout,Joep J. van Oosterhout,Amy Chen,Thomas S. Harrison,Adrienne K. Chan,Adrienne K. Chan +7 more
TL;DR: This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation, and remained with a permanent severe neurological deficit.