S
Sokoine Lesikari
Researcher at National Institute for Medical Research
Publications - 11
Citations - 396
Sokoine Lesikari is an academic researcher from National Institute for Medical Research. The author has contributed to research in topics: Flucytosine & Fluconazole. The author has an hindex of 5, co-authored 8 publications receiving 248 citations.
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Journal ArticleDOI
Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa
Síle F. Molloy,Cecilia Kanyama,Robert S. Heyderman,Angela Loyse,Charles Kouanfack,Duncan Chanda,Sayoki Mfinanga,Elvis Temfack,Shabir Lakhi,Sokoine Lesikari,Adrienne K. Chan,Neil Stone,Newton Kalata,Natasha Karunaharan,Katherine M Gaskell,Mary Peirse,Jayne Ellis,Chimwemwe Chawinga,Sandrine Lontsi,Jean-Gilbert Ndong,Philip Bright,Duncan Lupiya,Tao Chen,John S. Bradley,Jack Adams,Charles van der Horst,Joep J. van Oosterhout,Victor Sini,Yacouba Mapoure,Peter Mwaba,Tihana Bicanic,David G. Lalloo,Duolao Wang,Mina C. Hosseinipour,Olivier Lortholary,Shabbar Jaffar,Tom Harrison +36 more
TL;DR: Two treatment strategies that could be more sustainable in Africa than the standard of 2 weeks of amphotericin B plus flucytosine and more effective than the widely used fluconazole monotherapy were tested.
Journal ArticleDOI
Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries
Angela Loyse,Jessica Burry,Jennifer Cohn,Nathan Ford,Tom Chiller,Isabela Ribeiro,Sinata Koulla-Shiro,Janneth Mghamba,Angela Ramadhani,Rose Nyirenda,Sani H Aliyu,Douglas Wilson,Thuy Le,Rita O. Oladele,Sokoine Lesikari,Conrad Muzoora,Newton Kalata,Elvis Temfack,Yacouba Njankouo Mapoure,Victor Sini,Duncan Chanda,Meshack Shimwela,Shabir Lakhi,Jonathon Ngoma,Lilian Gondwe-Chunda,Chase Perfect,Amir Shroufi,Isabelle Andrieux-Meyer,Adrienne K. Chan,Adrienne K. Chan,Charlotte Schutz,Mina C. Hosseinipour,Charles van der Horst,Jeffrey D. Klausner,David R. Boulware,Robert S. Heyderman,David G. Lalloo,Jeremy N. Day,Joseph N Jarvis,Marcio L. Rodrigues,Shabbar Jaffar,David W. Denning,Chantal Migone,Megan Doherty,Olivier Lortholary,Françoise Dromer,Muirgen Stack,Síle F. Molloy,Tihana Bicanic,Joep J. van Oosterhout,Joep J. van Oosterhout,Peter Mwaba,Cecilia Kanyama,Charles Kouanfack,Sayoki Mfinanga,Nelesh P. Govender,Thomas S. Harrison +56 more
TL;DR: The potential to transform the management of HIV-related cryptococcal meningitis in resource-limited settings is substantial and sustainable access to essential medicines, including flucytosine and amphotericin B, in LMICs is paramount and the focus of this Personal View.
Journal ArticleDOI
Cryptococcal meningitis: A neglected NTD?
Síle F. Molloy,Tom Chiller,Gregory S. Greene,Jessica Burry,Nelesh P. Govender,Cecilia Kanyama,Sayoki Mfinanga,Sokoine Lesikari,Yacouba Mapoure,Charles Kouanfack,Victor Sini,Elvis Temfack,David R. Boulware,Françoise Dromer,David W. Denning,Jeremy N. Day,Neil Stone,Tihana Bicanic,Joseph N Jarvis,Joseph N Jarvis,Olivier Lortholary,Thomas S. Harrison,Shabbar Jaffar,Angela Loyse +23 more
TL;DR: Citation for published version (APA): Molloy, S. F., Chiller, T., Greene, G. S., Burry, J., Govender, N. N., Stone,N.
Journal ArticleDOI
Integrated care for human immunodeficiency virus, diabetes and hypertension in Africa
Anupam Garrib,Josephine Birungi,Sokoine Lesikari,Ivan Namakoola,Tsi Njim,Luis E. Cuevas,Louis W. Niessen,Kenneth Mugisha,Gerald Mutungi,Janneth Mghamba,Kaushik Ramaiya,Shabbar Jaffar,Sayoki Mfinanga,Moffat J. Nyirenda +13 more
TL;DR: Both HIV and NCD services must expand within a resource-constrained environment and policymakers are in urgent need of evidence to guide cost-effective and acceptable changes in these health services.
Journal ArticleDOI
Short-term Mortality Outcomes of HIV-Associated Cryptococcal Meningitis in Antiretroviral Therapy-Naïve and -Experienced Patients in Sub-Saharan Africa.
Newton Kalata,Jayne Ellis,Cecilia Kanyama,Charles Kuoanfank,Elvis Temfack,Sayoki Mfinanga,Sokoine Lesikari,Duncan Chanda,Shabir Lakhi,Tinashe K. Nyazika,Adrienne K. Chan,Adrienne K. Chan,Joep J van Oosterhout,Tao Chen,Mina C. Hosseinipour,Olivier Lortholary,Duolao Wang,Shabbar Jaffar,Angela Loyse,Robert S. Heyderman,Thomas S Harrison,Thomas S Harrison,Síle F Molloy +22 more
TL;DR: There were no significant differences in mortality at 2 and 10 weeks between ART-naïve and -experienced patients and between ART and ART- Experienced patients according to duration on ART.