E
Eden V. Barragan
Researcher at University of California, Davis
Publications - 10
Citations - 628
Eden V. Barragan is an academic researcher from University of California, Davis. The author has contributed to research in topics: NMDA receptor & Serine racemase. The author has an hindex of 6, co-authored 8 publications receiving 352 citations. Previous affiliations of Eden V. Barragan include University of California, Irvine & University of California, Berkeley.
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Journal ArticleDOI
Psychedelics Promote Structural and Functional Neural Plasticity
Calvin Ly,Alexandra C. Greb,Lindsay P. Cameron,Jonathan M. Wong,Eden V. Barragan,Paige C. Wilson,Kyle F. Burbach,Sina Soltanzadeh Zarandi,Alexander Sood,Michael R. Paddy,Whitney C. Duim,Megan Y. Dennis,A. Kimberley McAllister,Kassandra M. Ori-McKenney,John A. Gray,David E. Olson +15 more
TL;DR: It is reported that, like ketamine, serotonergic psychedelics are capable of robustly increasing neuritogenesis and/or spinogenesis both in vitro and in vivo.
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Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current
Ryan J. Schutte,Soleil S. Schutte,Jacqueline Algara,Eden V. Barragan,Jeff Gilligan,Cynthia Staber,Yiannis A. Savva,Martin A. Smith,Robert A. Reenan,Diane K. O'Dowd +9 more
TL;DR: Electrophysiological studies of GABAergic interneurons in the brains of adult DS flies reveal, for the first time in an in vivo model system, that a missense DS mutation causes a constitutive and conditional reduction in sodium current activity and repetitive firing.
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Model systems for studying cellular mechanisms of SCN1A related epilepsy
TL;DR: In this article, the authors review what has been learned about cellular mechanisms and potential new therapies from these model systems, with a particular emphasis on the novel model system of knock in Drosophila and a look toward the future with expanded use of patient-specific induced pluripotent stem cell derived neurons.
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Activity-Dependent Palmitoylation Controls SynDIG1 Stability, Localization, and Function
Inderpreet Kaur,Vladimir Yarov-Yarovoy,Lyndsey M. Kirk,Kristopher E. Plambeck,Eden V. Barragan,Eric S. Ontiveros,Elva D Diaz +6 more
TL;DR: It is demonstrated that activity-dependent palmitoylation of SynDIG1 is regulated by neuronal activity, and plays a critical role in regulating its stability and subcellular localization, and thereby its function.
Journal ArticleDOI
Postsynaptic Serine Racemase Regulates NMDA Receptor Function.
Jonathan M. Wong,Oluwarotimi Folorunso,Eden V. Barragan,Cristina Berciu,Theresa L. Harvey,Joseph T. Coyle,Darrick T. Balu,John A. Gray +7 more
TL;DR: An age-dependent dendritic and postsynaptic localization of SR and d-serine in mouse CA1 pyramidal neurons is shown and a cell-autonomous role for SR in regulating synaptic NMDAR function at Schaffer collateral (CA3)-CA1 synapses is demonstrated, suggesting a possible autocrine mode of d-Serine action at synapses.