E
Edward B. Ziff
Researcher at New York University
Publications - 136
Citations - 18236
Edward B. Ziff is an academic researcher from New York University. The author has contributed to research in topics: AMPA receptor & PDZ domain. The author has an hindex of 60, co-authored 134 publications receiving 17745 citations. Previous affiliations of Edward B. Ziff include Howard Hughes Medical Institute.
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Sucrose withdrawal induces depression and anxiety-like behavior by Kir2.1 upregulation in the nucleus accumbens
TL;DR: In the nucleus accumbens of sucrose withdrawal animals, dopamine levels and cAMP response element binding protein (CREB) activity were significantly reduced, while the inwardly rectifying K+ channel, Kir2.1, was significantly elevated.
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Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.
Yukio Akaneya,Kazuhiro Sohya,Akihiko Kitamura,Akihiko Kitamura,Fumitaka Kimura,Chris Washburn,Renping Zhou,Ipe Ninan,Tadaharu Tsumoto,Edward B. Ziff +9 more
TL;DR: Ephrin-A5 and EphA5 signals play a necessary, activity-independent role in the initiation of the early phases of synaptogenesis, and may be the developmental switch that induces expression of AMPAR and their interacting proteins and the transition to activity-dependent synaptic regulation.
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The amino-terminal region of the adenovirus serotype 5 E1a protein performs two separate functions when expressed in primary baby rat kidney cells.
D H Smith,Edward B. Ziff +1 more
TL;DR: It is shown that region 1 provides two distinct functions in infected primary rodent cells, one function is essential for induction of cell DNA synthesis, and the other is essential with a requirement for the DNA induction function in focus formation.
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Synaptic Autoregulation by Metalloproteases and γ-Secretase
Sophie Restituito,Latika Khatri,Ipe Ninan,Paul M. Mathews,Xin Liu,Richard J. Weinberg,Edward B. Ziff +6 more
TL;DR: It is suggested that activity-dependent substrate cleavage by synaptic metalloproteases and γ-secretase modifies synaptic transmission, providing a novel form of synaptic autoregulation.
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AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene.
TL;DR: Investigation of the roles of two elements of the TH promoter shows that both elements can function independently and contribute strongly to TH promoter basal activity in PC12 cells, suggesting that CRE-associated factors, including CBP, are not major regulators in the OB.